catalog number :
MBS421265
products full name :
Goat anti-EIF2C1 / AGO1 Antibody
products short name :
EIF2C1/AGO1
products name syn :
EIF2C1; eukaryotic translation initiation factor 2C; 1; AGO1; EIF2C; GERP95; Q99; Golgi Endoplasmic Reticulum protein 95 kDa; argonaute 1; putative RNA-binding protein Q99; EIF2C1; eukaryotic translation initiation factor 2C, 1; AGO1; EIF2C; GERP95; Q99; Golgi Endoplasmic Reticulum protein 95 kDa; argonaute 1; putative RNA-binding protein Q99
other names :
protein argonaute-1; Protein argonaute-1; protein argonaute-1; hAgo1; eIF2C 1; eIF-2C 1; argonaute1; argonaute 1; putative RNA-binding protein Q99; Golgi Endoplasmic Reticulum protein 95 kDa; eukaryotic translation initiation factor 2C, 1; argonaute RISC catalytic component 1; Argonaute RISC catalytic component 1; Eukaryotic translation initiation factor 2C 1; eIF-2C 1; eIF2C 1; Putative RNA-binding protein Q99
products gene name :
EIF2C1
other gene names :
AGO1; AGO1; Q99; EIF2C; EIF2C1; GERP95; EIF2C1; Argonaute1; hAgo1; eIF-2C 1; eIF2C 1
uniprot entry name :
AGO1_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
KNASYNLDPYIQEF
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB-Trf)
app notes :
Western Blot: In transfected HEK293 transiently expressing human EIF2C1bands of approx. 110kDa and 35kDa are observed. The 110kDa band is not observed in the non-transfected HEK293. The calculated molecular size is 97.2kDa according to NP_036331.1. Recommended concentration, 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-KNASYNLDPYIQEF, from the internal region of the protein sequence according to NP_036331.1. Corresponding Immunizing Peptide: Catalog #MBS426350
other info2 :
Important Note: This product is not expected to cross-react with EIF2C2, EIF2C3 and EIF2C4.
ncbi acc num :
NP_036331.1
ncbi gb acc num :
NM_012199.2
ncbi mol weight :
97,214 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Ca2+ Pathway 941399!!Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Disease Pathway 530764!!Downstream Signal Transduction Pathway 106385!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 576250!!Downstream Signaling Of Activated FGFR Pathway 160957
ncbi summary :
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and argonaute 4. [provided by RefSeq, Jul 2008]