product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-NUMB Antibody
catalog :
MBS421261
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, dog, cow
application :
western blot, immunocytochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS421261
products type :
Antibody
products full name :
Goat anti-NUMB Antibody
products short name :
NUMB
products name syn :
NUMB; numb homolog (Drosophila); S171; numb homolog; NUMB; numb homolog (Drosophila); S171; numb homolog
other names :
protein numb homolog isoform 1; Protein numb homolog; protein numb homolog; h-Numb; numb homolog (Drosophila); Protein S171
products gene name :
NUMB
other gene names :
NUMB; NUMB; S171; C14orf41; c14_5527; h-Numb
uniprot entry name :
NUMB_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Dog, Cow
sequence length :
651
sequence :
PFSSDLQKTFEIEL
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
app notes :
Western Blot: Approx 80kDa band observed in Mouse Brain lysates (calculated MW of 70.8kDa according to NP_001005743.1). Recommended concentration: 0.03-0.1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000. Immunocytochemsitry/Immunofluorescence: This antibody has been successfully used in mouse hematopoetic stem cells, in Mouse Embryonic brain tissue and in Human keratinocytes. Immunoprecipitation:An anonymous customer found positive results in IP on Mouse Embryo.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-PFSSDLQKTFEIEL, from the C Terminus of the protein sequence according to NP_001005743.1; 001005744.1; NP_003735; NP_001005745.1. Corresponding Immunizing Peptide: Catalog #MBS426388
other info2 :
Important Note: This antibody is expected to recognize all reported isoforms (NP_001005743.1, 001005744.1, NP_003735, NP_001005745.1). It is also likely to cross-react with Numblike (NUMBL, GeneID: 9253) which has a very similar C-Terminus, although this has not yet been tested experimentally.
ncbi gi num :
54144625
ncbi acc num :
NP_001005743.1
ncbi gb acc num :
NM_001005743.1
ncbi mol weight :
37,396 Da
ncbi pathways :
Activated NOTCH1 Transmits Signal To The Nucleus Pathway 576270!!Axon Guidance Pathway 105688!!Delta-Notch Signaling Pathway 198879!!Developmental Biology Pathway 477129!!Disease Pathway 530764!!FBXW7 Mutants And NOTCH1 In Cancer Pathway 771596!!L1CAM Interactions Pathway 161003!!Notch Signaling Pathway 198891!!Notch Signaling Pathway 83062!!Notch Signaling Pathway 169345
ncbi summary :
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!