catalog number :
MBS421254
products full name :
Goat anti-Stearoyl-CoA desaturase Antibody
products short name :
Stearoyl-CoA desaturase
products name syn :
SCD; SCD1; HGNC:10571; FADS5; PRO0998; acyl-CoA desaturase; delta-9-desaturase; fatty acid desaturase; predicted protein of HQ0998; stearoyl-CoA desaturase; SCD; SCD1; HGNC:10571; FADS5; PRO0998; acyl-CoA desaturase; delta-9-desaturase; fatty acid desaturase; predicted protein of HQ0998; stearoyl-CoA desaturase
other names :
acyl-CoA desaturase; Acyl-CoA desaturase; acyl-CoA desaturase; delta-9 desaturase; delta-9-desaturase; delta(9)-desaturase; fatty acid desaturase; predicted protein of HQ0998; stearoyl-CoA desaturase opposite strand; stearoyl-CoA desaturase (delta-9-desaturase); Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase; Stearoyl-CoA desaturase
other gene names :
SCD; SCD; SCD1; FADS5; SCDOS; MSTP008; Delta-9 desaturase
uniprot entry name :
ACOD_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Liver shows textured cytoplam staining in hepatocytes. Recommended concentration, 5-10ug/ml. Western Blot: Preliminary experiments gave an approx 30kDa band in Human Adipose, Brain and Liver lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 41.5kDa according to NP_005054.3. The 30kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-RIKRTGDGNYKSG, from the C Terminus of the protein sequence according to NP_005054.3.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425292
ncbi acc num :
NP_005054.3
ncbi gb acc num :
NM_005063.4
ncbi mol weight :
41,523 Da
ncbi pathways :
AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipogenesis Pathway 198832!!Biosynthesis Of Unsaturated Fatty Acids Pathway 83034!!Biosynthesis Of Unsaturated Fatty Acids Pathway 429!!Fatty Acid Biosynthesis Pathway 198873!!Fatty Acid Metabolism Pathway 868084!!Fatty Acid Metabolism Pathway 878045!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450
ncbi summary :
This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Feb 2012]