catalog number :
MBS421232
products full name :
Goat anti-SLIMMER / FHL1 isoform B Antibody
products short name :
SLIMMER/FHL1 isoform B
products name syn :
FHL1; KYO-T; SLIM1; bA535K18.1; four and a half LIM domains 1; Four-and-a-half LIM domains 1; bA535K18.1 (LIM protein SLIMMER); RP11-535K18.1; FHL1A; FHL1B; FLH1A; KYOT; MGC111107; SLIMMER;; XMPMA; LIM protein SLIMMER; four-and-a-half Lin11; Isl-1 and Mec-3 domains 1; skeletal muscle LIM-protein1; Goat Anti-FHL1 / SLIM1; FHL1; KYO-T; SLIM1; bA535K18.1; four and a half LIM domains 1; Four-and-a-half LIM domains 1; bA535K18.1 (LIM protein SLIMMER); RP11-535K18.1; FHL1A; FHL1B; FLH1A; KYOT; MGC111107; SLIMMER, XMPMA; LIM protein SLIMMER; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; skeletal muscle LIM-protein1
other names :
LIM protein SLIMMER; Four and a half LIM domains protein 1; four and a half LIM domains protein 1; LIM protein SLIMMER; skeletal muscle LIM-protein 1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; four and a half LIM domains 1; Skeletal muscle LIM-protein 1; SLIM; SLIM-1
products gene name :
FHL1
other gene names :
FHL1; FHL1; KYOT; SLIM; FHL-1; FHL1A; FHL1B; FLH1A; SLIM1; XMPMA; SLIM-1; SLIMMER; SLIM1; FHL-1; SLIM; SLIM-1
uniprot entry name :
FHL1_HUMAN
reactivity :
Human, Mouse, Dog
sequence :
CTVSRVSHPVSKARK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 30kDa band observed in Human Heart lysates is consistent with literature (PMID:10480922; calculated MW of 36.3kDa according to AAC72886). Recommended concentration: 0.01-0.1ug/ml. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence CTVSRVSHPVSKARK, from the internal region of the protein sequence according to AAC72886.1. Corresponding Immunizing Peptide: Catalog #MBS425113
other info2 :
Important Note: This antibody is specific for the FHL-1 isoform B (SLIMMER) and is expected to recognise an epitope corresponding to aa 233-246 of human SLIMMER protein.
ncbi acc num :
AAC72886.1
ncbi mol weight :
33,579 Da
ncbi pathways :
Delta-Notch Signaling Pathway 198879
ncbi summary :
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009]