catalog number :
MBS421224
products full name :
Goat anti-FOXO3A / FOXO3 / FKHRL1 Antibody
products short name :
FOXO3A/FOXO3/FKHRL1
products name syn :
FOXO3A; FKHRL1; AF6q21; FKHRL1P2; MGC12739; MGC31925; DKFZp781A0677; forkhead box O3A; forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1; forkhead; Drosophila; homolog of; in rhabdomyosarcoma-like 1; FOXO3; forkhead box O3; FOXO2; forkhead homolog (rhabdomyosarcoma) like 1; forkhead; Drosophila; homolog of; in rhabdomyosarcoma-like 1; FOXO3; FOXO3A; FKHRL1; AF6q21; FKHRL1P2; MGC12739; MGC31925; DKFZp781A0677; forkhead box O3A; forkhead (Drosophila) homolog; FOXO2; forkhead homolog (rhabdomyosarcoma) like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1 (rhabdomyosarcoma) like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; forkhead box O3
other names :
forkhead box protein O3; Forkhead box protein O3; forkhead box protein O3; forkhead box O3A; forkhead in rhabdomyosarcoma-like 1; forkhead homolog (rhabdomyosarcoma) like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; forkhead box O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
products gene name :
FOXO3
other gene names :
FOXO3; FOXO3; FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; FKHRL1; FOXO3A
uniprot entry name :
FOXO3_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 90kDa band observed in human Brain and Heart lysates (calculated MW of 71.3kDa according to NP_001446 and NP_963853). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-GAKQASSQSWVPG, from the C Terminus of the protein sequence according to NP_001446.1. Corresponding Immunizing Peptide: Catalog #MBS425733
other info2 :
Important Note: Both variants represent identical protein (NP_001446.1and NP_963853.1).
ncbi acc num :
NP_001446.1
ncbi gb acc num :
NM_001455.3
ncbi mol weight :
48,406 Da
ncbi pathways :
AKT Phosphorylates Targets In The Nucleus Pathway 106476!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adaptive Immune System Pathway 366160!!BDNF Signaling Pathway 712093!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class I PI3K Signaling Events Pathway 138022!!Class I PI3K Signaling Events Mediated By Akt Pathway 138020!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535
ncbi summary :
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]