catalog number :
MBS421223
products full name :
Goat anti-PPP2CA / PPP2CB Antibody
products short name :
PPP2CA/PPP2CB
products name syn :
PPP2CA; protein phosphatase 2 (formerly 2A); catalytic subunit; alpha isoform; PP2Ac; PP2CA; RP-C; PP2A-alpha; protein phosphatase 2; catalytic subunit; alpha isoform; replication protein C; serine/threonine protein phosphatase 2A; catalytic subunit; alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PPP2CB; protein phosphatase 2 (formerly 2A); catalytic subunit; beta isoform; PP2CB; PP2A-beta; protein phosphatase 2; catalytic subunit; beta isoform; protein phosphatase type 2A catalytic subunit; serine/threonine protein phosphatase 2A; catalytic subunit; beta isoform; PPP2CA; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; PP2Ac; PP2CA; RP-C; PP2A-alpha; protein phosphatase 2, catalytic subunit, alpha isoform; replication protein C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PPP2CB; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; PP2CB; PP2A-beta; protein phosphatase 2, catalytic subunit, beta isoform; protein phosphatase type 2A catalytic subunit; serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform
other names :
serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; replication protein C; protein phosphatase 2A catalytic subunit, alpha isoform; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; Replication protein C; RP-C
products gene name :
PPP2CA/PPP2CB
other gene names :
PPP2CA; PPP2CA; RP-C; PP2Ac; PP2CA; PP2Calpha; PP2A-alpha; RP-C
uniprot entry name :
PP2AA_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Rabbit, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 35kDa band observed in Human Brain (Cerebellum), Mouse Brain and Rat Brain lysates (calculated MW of 35.6kDa according to NP_002706.1and NP_004147.1). Recommended concentration: 0.05-0.2ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-EPHVTRRTPDYFL, from the C Terminus of the protein sequence according to NP_002706.1; NP_004147.1. Corresponding Immunizing Peptide: Catalog #MBS426027
other info2 :
Important Note: Two variants NP_001009552.1 and NP_004147.1 represent identical protein.
ncbi acc num :
NP_002706.1
ncbi gb acc num :
NM_002715.2
ncbi mol weight :
29,735 Da
ncbi pathways :
AMER1 Mutants Destabilize The Destruction Complex Pathway 1016198!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway 1016193!!APC Truncation Mutants Have Impaired AXIN Binding Pathway 1016194!!AXIN Missense Mutants Destabilize The Destruction Complex Pathway 1016197!!AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway 1016195!!Activated TLR4 Signalling Pathway 106400!!Adaptive Immune System Pathway 366160!!Adrenergic Signaling In Cardiomyocytes Pathway 908257
ncbi summary :
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008]