Goat anti-AKR1C3 Antibody | MyBioSource MBS421221 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-AKR1C3 Antibody

catalog :

MBS421221

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS421221

products type :

Antibody

products full name :

Goat anti-AKR1C3 Antibody

products short name :

AKR1C3

products name syn :

AKR1C3; DD3; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS; KIAA0119; aldo-keto reductase family 1; member C3 (3-alpha hydroxysteroid dehydrogenase; type II); prostaglandin F synthase; dihydrodiol dehydrogenase 3; chlordecone reductase homolog; hydroxysteroid (17-beta) dehydrogenase 5; type IIb 3-alpha hydroxysteroid dehydrogenase; trans-1; 2-dihydrobenzene-1; 2-diol dehydrogenase; DDX; aldo-keto reductase family 1; member C3; chlordecone reductase; dihydrodiol dehydrogenase X; type II 3a-hydroxysteroid dehydrogenase; type IIb 3-alpha hydroxysteroid dehydrogenase; DD3; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS; KIAA0119; aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II); prostaglandin F synthase; dihydrodiol dehydrogenase 3; chlordecone reductase homolog; hydroxysteroid (17-beta) dehydrogenase 5; type IIb 3-alpha hydroxysteroid dehydrogenase; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; DDX; aldo-keto reductase family 1, member C3; chlordecone reductase; dihydrodiol dehydrogenase X; type II 3a-hydroxysteroid dehydrogenase; type IIb 3-alpha hydroxysteroid dehydrogenase

other names :

aldo-keto reductase family 1 member C3 isoform 1; Aldo-keto reductase family 1 member C3; aldo-keto reductase family 1 member C3; indanol dehydrogenase; prostaglandin F synthase; 3-alpha-HSD type II, brain; dihydrodiol dehydrogenase 3; dihydrodiol dehydrogenase X; chlordecone reductase homolog HAKRb; testosterone 17-beta-dehydrogenase 5; 3-alpha hydroxysteroid dehydrogenase, type II; type IIb 3-alpha hydroxysteroid dehydrogenase; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II); aldo-keto reductase family 1, member C3; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2 (EC:1.1.1.357); 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Indanol dehydrogenase (EC:1.1.1.112); Prostaglandin F synthase (EC:1.1.1.188); PGFS; Testosterone 17-beta-dehydrogenase 5 (EC:1.1.1.239, EC:1.1.1.64); Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC:1.3.1.20)

products gene name :

AKR1C3

other gene names :

AKR1C3; AKR1C3; DD3; DDX; PGFS; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS; DDH1; HSD17B5; KIAA0119; PGFS; 17-beta-HSD 5; 3-alpha-HSD type 2; DD-3; DD3; PGFS

uniprot entry name :

AK1C3_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human

sequence length :

323

sequence :

CFASHPNYPYSDEY

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Western Blot: Approx 35kDa band observed in human liver and human breast lysates (calculated MW of 36.9kDa according to NP_003730). Recommended concentration: 0.01-0.1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

other info1 :

Epitope: C Terminus. Immunogen: Peptide with sequence CFASHPNYPYSDEY, from the C Terminus of the protein sequence according to NP_003730.4.

other info2 :

Corresponding Immunizing Peptide: Catalog #MBS425848

ncbi gi num :

24497583

ncbi acc num :

NP_003730.4

ncbi gb acc num :

NM_003739.5

ncbi mol weight :

23,364 Da

ncbi pathways :

Arachidonic Acid Metabolism Pathway 82991!!Arachidonic Acid Metabolism Pathway 685553!!Arachidonic Acid Metabolism Pathway 366!!Benzo(a)pyrene Metabolism Pathway 198911!!Bile Acid And Bile Salt Metabolism Pathway 106144!!Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976

ncbi summary :

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

size :

0.1 mg

price :

290 USD

more info or order :

MyBioSource product webpage