catalog number :
MBS421211
products full name :
Goat anti-FYN Antibody
products short name :
FYN
products name syn :
FYN; SLK; SYN; MGC45350; FYN oncogene related to SRC; FGR; YES; src-like kinase; c-syn protooncogene; tyrosine kinase p59fyn(T); src/yes-related novel gene; OKT3-induced calcium influx regulator; proto-oncogene tyrosine-protein kinase fyn; RP1-66H14.1; OTTHUMP00000017917; protein-tyrosine kinase fyn; src-like kinase; FYN; SLK; SYN; MGC45350; FYN oncogene related to SRC, FGR, YES; src-like kinase; c-syn protooncogene; tyrosine kinase p59fyn(T); src/yes-related novel gene; OKT3-induced calcium influx regulator; proto-oncogene tyrosine-protein kinase fyn; RP1-66H14.1; OTTHUMP00000017917; protein-tyrosine kinase fyn; src-like kinase
other names :
tyrosine-protein kinase Fyn isoform a; Tyrosine-protein kinase Fyn; tyrosine-protein kinase Fyn; src-like kinase; proto-oncogene Syn; c-syn protooncogene; proto-oncogene c-Fyn; src/yes-related novel; tyrosine kinase p59fyn(T); FYN oncogene related to SRC, FGR, YES; OKT3-induced calcium influx regulator; FYN proto-oncogene, Src family tyrosine kinase; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn
other gene names :
FYN; FYN; SLK; SYN; p59-FYN; SLK
uniprot entry name :
FYN_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 55-60kDa band observed in Jurkat, A431 and NIH-3T3 lysates (predicted MW of 62kDa according to NP_002028.1). Recommended for use at 0.2-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence VQCKDKEATKLTE, from the N Terminus of the protein sequence according to NP_002028.1; NP_694592.1; NP_694593.1. Corresponding Immunizing Peptide: Catalog #MBS426524
other info2 :
Important Note: This antibody is expected to recognise all three reported isoforms (as represented by NP_002028.1; NP_694592.1; NP_694593.1).
ncbi acc num :
NP_002028.1
ncbi gb acc num :
NM_002037.5
ncbi mol weight :
54,513 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Alpha-synuclein Signaling Pathway 137913!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Angiopoietin Receptor Tie2-mediated Signaling Pathway 137917!!Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway 576249!!Axon Guidance Pathway 83065!!Axon Guidance Pathway 476!!Axon Guidance Pathway 105688
ncbi summary :
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]