catalog number :
MBS421194
products full name :
Goat anti-NGFR Antibody
products short name :
NGFR
products name syn :
NGFR; nerve growth factor receptor (TNFR superfamily; member 16); HGNC:7809; TNFRSF16; p75(NTR); p75NTR; CD271; low affinity nerve growth factor receptor; low-affinity nerve growth factor receptor; Gp80-LNGFR; nerve growth factor receptor; Goat Anti-p75NTR / CD271 (aa202-215); NGFR; nerve growth factor receptor (TNFR superfamily, member 16); HGNC:7809; TNFRSF16; p75(NTR); p75NTR; CD271; Gp80-LNGFR; low affinity nerve growth factor receptor; low-affinity nerve growth factor receptor; nerve growth factor receptor
other names :
tumor necrosis factor receptor superfamily member 16; Tumor necrosis factor receptor superfamily member 16; tumor necrosis factor receptor superfamily member 16; p75 ICD; NGF receptor; TNFR superfamily, member 16; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD_antigen: CD271
products gene name :
NGFR
other gene names :
NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16; NGF receptor
uniprot entry name :
TNR16_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 75kDa band observed in Human Duodenum and Human Heart lysates (calculated MW of 45.2kDa according to NP_4804). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Nykjaer et al, Curr Opin Neurobiol. 2005 Feb;15(1):49-57). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-AKREEVEKLLNG, from the internal region of the protein sequence according to NP_002498.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428590
ncbi acc num :
NP_002498.1
ncbi gb acc num :
NM_002507.3
ncbi mol weight :
35,767 Da
ncbi pathways :
Axonal Growth Inhibition (RHOA Activation) Pathway 106454!!Axonal Growth Stimulation Pathway 106453!!BDNF Signaling Pathway 712093!!Cell Death Signalling Via NRAGE, NRIF And NADE Pathway 106443!!Ceramide Signalling Pathway 106451!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!NADE Modulates Death Signalling Pathway 106446!!NF-kB Is Activated And Signals Survival Pathway 106450!!NFG And ProNGF Binds To P75NTR Pathway 106442
ncbi summary :
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]