catalog number :
MBS421189
products full name :
Goat anti-LAMA3 Antibody
products short name :
LAMA3
products name syn :
LAMA3; laminin; alpha 3; HGNC:6483; E170; LAMNA; LOCS; BM600 150kD subunit; epiligrin 170 kda subunit; epiligrin alpha 3 subunit; kalinin 165kD subunit; laminin alpha 3 subunit; laminin alpha 3b chain; laminin; alpha 3 (nicein (150kD); kalinin (165kD); BM600 (150kD); epilegrin); laminin-5 alpha 3 chain; nicein 150kD subunit; BM600; lama3a; LAMA3; laminin, alpha 3; HGNC:6483; E170; LAMNA; LOCS; BM600 150kD subunit; epiligrin 170 kda subunit; epiligrin alpha 3 subunit; kalinin 165kD subunit; laminin alpha 3 subunit; laminin alpha 3b chain; laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin); laminin-5 alpha 3 chain; nicein 150kD subunit; BM600; lama3a
other names :
laminin subunit alpha-3 isoform 1; Laminin subunit alpha-3; laminin subunit alpha-3; laminin A3; BM600 150kD subunit; nicein 150kD subunit; nicein subunit alpha; LAM3, alpha-3 subunit; kalinin 165kD subunit; kalinin subunit alpha; laminin-5 alpha 3 chain; laminin-5 subunit alpha; laminin-6 subunit alpha; laminin-7 subunit alpha; epiligrin 170 kda subunit; epiligrin alpha 3 subunit; laminin 5, alpha-3 subunit; laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin); laminin, alpha 3; Epiligrin 170 kDa subunit; E170; Epiligrin subunit alpha; Kalinin subunit alpha; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; Nicein subunit alpha
products gene name :
LAMA3
other gene names :
LAMA3; LAMA3; E170; LOCS; BM600; LAMNA; LAMNA; E170
uniprot entry name :
LAMA3_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments in human kidney, lung and skin lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Peptide ELISA: antibody detection limit dilution 1:2000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence NNQCHSSHKRRTK, from the internal region of the protein sequence according to NP_937762.1. Corresponding Immunizing Peptide: Catalog #MBS425643
other info2 :
Important Note: This antibody is expected to recognise isoform 1 (NP_937762.1) only.
ncbi acc num :
NP_937762.1
ncbi gb acc num :
NM_198129.1
ncbi mol weight :
184,054 Da
ncbi pathways :
Alpha6-Beta4 Integrin Signaling Pathway 198807!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Anchoring Fibril Formation Pathway 730307!!Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway 730306!!Cell Junction Organization Pathway 160966!!Cell-Cell Communication Pathway 477132!!Collagen Formation Pathway 645288!!Degradation Of The Extracellular Matrix Pathway 576263!!ECM Proteoglycans Pathway 833812
ncbi summary :
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]