catalog number :
MBS421179
products full name :
Goat anti-HADH / HADHSC Antibody
products short name :
HADH/HADHSC
products name syn :
HADH; HADHSC; hydroxyacyl-Coenzyme A dehydrogenase; HAD; HADH1; HHF4; M/SCHAD; MGC8392; SCHAD; L-3-hydroxyacyl-Coenzyme A dehydrogenase; L-3-hydroxyacyl-Coenzyme A dehydrogenase; short chain; HADH; HADHSC; hydroxyacyl-Coenzyme A dehydrogenase; HAD; HADH1; HHF4; M/SCHAD; MGC8392; SCHAD; L-3-hydroxyacyl-Coenzyme A dehydrogenase; L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain
other names :
hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform 2; Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; short-chain 3-hydroxyacyl-CoA dehydrogenase; L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain; medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; hydroxyacyl-CoA dehydrogenase; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase
products gene name :
HADH
other gene names :
HADH; HADH; HAD; HCDH; HHF4; HADH1; SCHAD; HADHSC; MSCHAD; HAD; HADHSC; SCHAD; HCDH
uniprot entry name :
HCDH_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx. 33kDa band observed in Human Heart, Muscle and Kidney lysates (calculated MW of 34.3kDa according to NP_005318.2). In transfected HEK293 transiently expressing HADH a band of approx. 38kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.01-0.03ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-YERGDASKEDID, from the internal region of the protein sequence according to NP_005318.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425675
ncbi acc num :
NP_005318.2
ncbi gb acc num :
NM_005327.3
ncbi mol weight :
36,051 Da
ncbi pathways :
Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway 106130!!Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway 106127!!Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway 106129!!Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway 106126!!Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway 106128!!Butanoate Metabolism Pathway 83007!!Butanoate Metabolism Pathway 391!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Fatty Acid Beta Oxidation Pathway 198865!!Fatty Acid Biosynthesis Pathway 198873
ncbi summary :
This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]