catalog number :
MBS421177
products full name :
Goat anti-ANILLIN / Scraps (C Terminus) Antibody
products short name :
ANILLIN/Scraps
products name syn :
ANLN; Scraps; ANILLIN; anillin; actin binding protein (scraps homolog; Drosophila); anillin (Drosophila Scraps homolog); actin binding protein; anillin; actin binding protein; DKFZp779A055; scra; Goat Anti-ANILLIN / Scraps (internal); Scraps; ANILLIN; anillin, actin binding protein (scraps homolog, Drosophila); anillin (Drosophila Scraps homolog), actin binding protein; anillin, actin binding protein; DKFZp779A055; scra
other names :
actin-binding protein anillin isoform 1; Actin-binding protein anillin; actin-binding protein anillin; anillin, actin binding protein
products gene name :
ANLN
other gene names :
ANLN; ANLN; scra; FSGS8; Scraps
uniprot entry name :
ANLN_HUMAN
reactivity :
Human, Mouse, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Kidney shows staining of nuclei in some cells of renal tubules. Recommended concentration, 3-10ug/ml. Western Blot: Preliminary experiments gave an approx 75kDa band in Mouse Brain lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 124kDa according to NP_061155.2. The 75kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence WQPDACYKPIGKP, from the C Terminus of the protein sequence according to NP_061155.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428552
ncbi acc num :
NP_061155.2
ncbi gb acc num :
NM_018685.4
ncbi mol weight :
120,016 Da
ncbi pathways :
RB In Cancer Pathway 920977
ncbi summary :
This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]