catalog number :
MBS421175
products full name :
Goat anti-CPT1B (isoform 1) Antibody
products short name :
CPT1B
products name syn :
CPT1B; carnitine palmitoyltransferase I, muscle; carnitine palmitoyltransferase 1B (muscle); CPT1-M; M-CPT1; KIAA1670; CPTI, muscle; carnitine O-palmitoyltransferase I, mitochondrial muscle isoform; carnitine palmitoyltransferase 1A (muscle); carnitine p; CPT1B antibody; carnitine palmitoyltransferase I; muscle antibody; carnitine palmitoyltransferase 1B (muscle) antibody; CPT1-M antibody; M-CPT1 antibody; KIAA1670 antibody; CPTI; muscle antibody; carnitine O-palmitoyltransferase I; mitochondrial muscle isoform antibody; carnitine palmitoyltransferase 1A (muscle) antibody; carnitine palmitoyltransferase 1B antibody; carnitine palmitoyltransferase 1B (muscle) antibody; CPT1M antibody; FLJ55729 antibody; FLJ58750 antibody; MCCPT1 antibody; MCPT1 antibody; carnitine palmitoyltransferase I-like antibody; CPT1B (isoform 1)
other names :
carnitine O-palmitoyltransferase 1, muscle isoform isoform a; Carnitine O-palmitoyltransferase 1, muscle isoform; carnitine O-palmitoyltransferase 1, muscle isoform; carnitine palmitoyltransferase 1B; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like protein
products gene name :
CPT1B
other gene names :
CPT1B; CPT1B; CPTI; CPT1M; MCPT1; CPT1-M; CPTI-M; M-CPT1; MCCPT1; KIAA1670; CPT1-M; CPT I; CPTI-M
uniprot entry name :
CPT1B_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Immunohistochemistry: In paraffin embedded Human Heart shows staining of myocardial fibres in longitudinal section. Recommended concentration, 3-5ug/ml. Western Blot: Preliminary experiments gave no signal but low background in human kidney and HepG2 lysates at up to 1ug/ml.
other info1 :
Immunogen: Peptide with sequence C-DIADLFQVPKAYS, from the C Terminus of the protein sequence according to NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1; NP_001138606.1; NP_001138608.1. Epitope: C Terminus
other info2 :
Note: This antibody is expected to recognise human isoforms a (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1), isoform c (NP_001138606.1) and isoform d (NP_001138608.1).
ncbi acc num :
NP_689452.1
ncbi gb acc num :
NM_152246.2
ncbi mol weight :
78,844 Da
ncbi pathways :
AMPK Signaling Pathway (198868); AMPK Signaling Pathway (989139); AMPK Signaling Pathway (992181); Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Fatty Acid Beta Oxidation Pathway (198865); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296); Fatty Acid Metabolism Pathway (868084)
ncbi summary :
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]
uniprot summary :
CPT1B: a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]. Protein type: Lipid Metabolism - fatty acid; Membrane protein, multi-pass; EC 2.3.1.21; Transferase; Membrane protein, integral. Chromosomal Location of Human Ortholog: 22q13.33. Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion. Molecular Function: carnitine O-palmitoyltransferase activity; protein binding. Biological Process: carnitine shuttle; fatty acid beta-oxidation