catalog number :
MBS421172
products full name :
Goat anti-Homeobox B13 Antibody
products short name :
Homeobox B13
products name syn :
homeobox B13; HOXB13; PSGD; homeo box B13; homeobox B13 antibody; HOXB13 antibody; PSGD antibody; homeo box B13 antibody; Homeobox B13; Homeobox B13
other names :
homeobox protein Hox-B13; Homeobox protein Hox-B13; homeobox protein Hox-B13; homeobox B13
products gene name :
HOXB13
other gene names :
HOXB13; HOXB13; PSGD
uniprot entry name :
HXB13_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 28kDa band observed in lysates of cell lines A431 and HeLa (calculated MW of 30.7kDa according to NP_006352.2). Recommended concentration: 0.1-0.3ug/ml.
other info1 :
Immunogen: Peptide with sequence C-KKVLAKVKNSATP, from the C Terminus of the protein sequence according to NP_006352.2. Epitope: C Terminus
ncbi acc num :
NP_006352.2
ncbi gb acc num :
NM_006361.5
ncbi mol weight :
30,676 Da
ncbi pathways :
Regulation Of Androgen Receptor Activity Pathway (138027)
ncbi summary :
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008]
uniprot summary :
HOXB13: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 17q21.2. Cellular Component: nucleoplasm; transcription factor complex. Molecular Function: sequence-specific DNA binding. Biological Process: angiogenesis; epidermis development; regulation of growth; regulation of transcription, DNA-dependent; response to testosterone stimulus; response to wounding; transcription, DNA-dependent