product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-AID Antibody
catalog :
MBS421169
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, cow
application :
western blot, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS421169
products type :
Antibody
products full name :
Goat anti-AID Antibody
products short name :
AID
products name syn :
AID; AICDA; activation-induced cytidine deaminase; ARP2; CDA2; HIGM2; activation-induced deaminase; integrated into Burkitt's lymphoma line Ramos; AID antibody; AICDA antibody; activation-induced cytidine deaminase antibody; ARP2 antibody; CDA2 antibody; HIGM2 antibody; activation-induced deaminase antibody; integrated into Burkitt 1s lymphoma line Ramos antibody
other names :
single-stranded DNA cytosine deaminase; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; activation-induced cytidine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase
products gene name :
AICDA
products gene name syn :
AID
other gene names :
AICDA; AICDA; AID; ARP2; CDA2; HIGM2; HEL-S-284; AID
uniprot entry name :
AICDA_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human, Pig, Cow
sequence length :
198
sequence :
RRKFLYQFKNVR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Approx 26kDa band observed in Human Lymph Node, Spleen and Tonsil lysates (calculated MW of 24. 0kDa according to NP_065712.1). Recommended concentration: 0.1-0.3ug/ml.
other info1 :
Immunogen: Peptide with sequence RRKFLYQFKNVR-C, from the N Terminus of the protein sequence according to NP_065712.1. Epitope: N Terminus
ncbi gi num :
10190700
ncbi acc num :
NP_065712.1
ncbi gb acc num :
NM_020661.2
ncbi mol weight :
22,614 Da
ncbi pathways :
IL4-mediated Signaling Events Pathway (137933); Intestinal Immune Network For IgA Production Pathway (128760); Intestinal Immune Network For IgA Production Pathway (128670); Primary Immunodeficiency Pathway (83125); Primary Immunodeficiency Pathway (537)
ncbi summary :
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]
uniprot summary :
AID: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class- switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Strongly expressed in lymph nodes and tonsils. Belongs to the cytidine and deoxycytidylate deaminase family. Protein type: EC 3.5.4.38; Hydrolase. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: cytoplasm; exosome (RNase complex); nucleus. Molecular Function: cytidine deaminase activity; protein binding; ubiquitin protein ligase binding; zinc ion binding. Biological Process: B cell differentiation; cytidine deamination; isotype switching; mRNA processing; somatic diversification of immunoglobulins; somatic hypermutation of immunoglobulin genes. Disease: Immunodeficiency With Hyper-igm, Type 2
size1 :
0.1 mg
price1 :
300 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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