catalog number :
MBS421165
products full name :
Goat anti-Integrin beta 5 Antibody
products short name :
Integrin beta 5
products name syn :
ITGB5; integrin, beta 5; FLJ26658; ITGB5 antibody; integrin; beta 5 antibody; FLJ26658 antibody; Integrin beta 5; Integrin beta 5
other names :
integrin beta-5; Integrin beta-5; integrin beta-5; integrin subunit beta 5
products gene name :
ITGB5
other gene names :
ITGB5; ITGB5
uniprot entry name :
ITB5_HUMAN
reactivity :
Tested: Human, Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
sequence :
TFNKFNKSYNGTVD
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000.
other info1 :
Immunogen: Peptide with sequence C-TFNKFNKSYNGTVD, from the C Terminus of the protein sequence according to NP_002204.2. Epitope: C Terminus
ncbi acc num :
NP_002204.2
ncbi gb acc num :
NM_002213.4
ncbi mol weight :
88,054 Da
ncbi pathways :
Adaptive Immune System Pathway (1269171); Antigen Processing-Cross Presentation Pathway (1269195); Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Class I MHC Mediated Antigen Processing Presentation Pathway (1269192); Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway (1269196); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); ECM Proteoglycans Pathway (1270256)
uniprot summary :
ITGB5: Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V. Interacts with MYO10. Belongs to the integrin beta chain family. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion. Chromosomal Location of Human Ortholog: 3q21.2. Cellular Component: cell surface; focal adhesion; phagocytic vesicle; plasma membrane; receptor complex. Molecular Function: protein binding; viral receptor activity. Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; cell-matrix adhesion; entry of virus into host cell; extracellular matrix organization and biogenesis; integrin-mediated signaling pathway; muscle contraction; stress fiber formation; transforming growth factor beta receptor signaling pathway