Goat anti-CGI58/ABHD5 Antibody | MyBioSource MBS421157 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-CGI58/ABHD5 Antibody

catalog :

MBS421157

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS421157

products type :

Antibody

products full name :

Goat anti-CGI58/ABHD5 Antibody

products short name :

CGI58/ABHD5

products name syn :

ABHD5; CGI58 protein; aCGI58; bhydrolase domain containing 5; CDS; IECN2; MGC8731; NCIE2; ABHD5 antibody; CGI58 protein antibody; aCGI58 antibody; bhydrolase domain containing 5 antibody; CDS antibody; IECN2 antibody; MGC8731 antibody; NCIE2 antibody; CGI58 / ABHD5

other names :

1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; abhydrolase domain containing 5; Abhydrolase domain-containing protein 5; Lipid droplet-binding protein CGI-58

products gene name :

ABHD5

products gene name syn :

CGI58

other gene names :

ABHD5; ABHD5; CDS; CGI58; IECN2; NCIE2; NCIE2

uniprot entry name :

ABHD5_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human. Mouse, Cow; Expected from sequence similarity: Human, Mouse, Rat, Dog

sequence length :

349

sequence :

FPERPDLADQDR

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 16000.

other info1 :

Immunogen: Peptide with sequence C-FPERPDLADQDR, from the internal region of the protein sequence according to NP_057090.2. Epitope: Internal region

other info2 :

Note: This antibody is not expected to cross-react with ABHD4.

ncbi gi num :

31542303

ncbi acc num :

NP_057090.2

ncbi gb acc num :

NM_016006.4

ncbi mol weight :

39,096 Da

ncbi pathways :

CDP-diacylglycerol Biosynthesis Pathway (142255); Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway (1270009); Lipid Digestion, Mobilization, And Transport Pathway (1270002); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Regulation Of Lipolysis In Adipocytes Pathway (1222950); Triacylglycerol Biosynthesis Pathway (142242)

ncbi summary :

The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. [provided by RefSeq, Jul 2008]

uniprot summary :

ABHD5: a lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Colocalized with PLIN and ADFP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA. Defects cause neutral lipid storage disease (NLSD), an autosomal recessive disorder characterized by the excessive accumulation of neutral lipids in multiple tissues, and Chanarin-Dorfman syndrome (CDS), a triglyceride storage disease with impaired long-chain fatty acid oxidation and icthyosis. CDS is an autosomal recessive inborn error of lipid metabolism with multisystemic accumulation of triglycerides although plasma concentrations are normal. Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons. Protein type: Transferase; Lipase; EC 2.3.1.51. Chromosomal Location of Human Ortholog: 3p21. Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; lipid particle; nucleus. Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; lysophosphatidic acid acyltransferase activity; triacylglycerol lipase activity. Biological Process: cell differentiation; fatty acid metabolic process; phosphatidic acid biosynthetic process; positive regulation of lipoprotein lipase activity. Disease: Chanarin-dorfman Syndrome

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage