product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-DAP10 / HCST Antibody
catalog :
MBS421147
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421147
products type :
Antibody
products full name :
Goat anti-DAP10 / HCST Antibody
products short name :
DAP10/HCST
products name syn :
HCST; DAP10; hematopoietic cell signal transducer; KAP10; PIK3AP; DNAX-activation protein 10; phosphoinositide-3-kinase adaptor protein; HCST; DAP10; hematopoietic cell signal transducer; KAP10; PIK3AP; DNAX-activation protein 10; phosphoinositide-3-kinase adaptor protein
other names :
hematopoietic cell signal transducer isoform 1; Hematopoietic cell signal transducer; hematopoietic cell signal transducer; kinase assoc protein; membrane protein DAP10; DNAX-activation protein 10; kinase assoc pro of ~10kDa; transmembrane adapter protein KAP10; phosphoinositide-3-kinase adaptor protein; hematopoietic cell signal transducer; DNAX-activation protein 10; Membrane protein DAP10; Transmembrane adapter protein KAP10
products gene name :
HCST
other gene names :
HCST; HCST; DAP10; KAP10; PIK3AP; DAP10; KAP10; PIK3AP
uniprot entry name :
HCST_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat
sequence length :
93
sequence :
RSPAQEDGKVYIN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 40kDa band observed in human spleen lysates (calculated MW of 9.5kDa according to NP_055081.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Wu et al, Science. 1999 Jul 30;285(5428):730-2.; PMID: 10426994). Recommended concentration: 0.2-0.6ug/ml.
An additional band of unknown identity was also consistently observed at 100kDa. This band was successfully blocked by incubation with the immunising peptide. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-RSPAQEDGKVYIN, from the C Terminus of the protein sequence according to NP_055081.1; NP_001007470.1. Corresponding Immunizing Peptide: Catalog #MBS426124
other info2 :
Important Note: This antibody is expected to recognise isoform 1 (NP_055081.1) but it may recognize isoform 2 lacking residue E81 (NP_001007470.1).
ncbi gi num :
15826850
ncbi acc num :
NP_055081.1
ncbi gb acc num :
NM_014266.3
ncbi mol weight :
9,360 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413!!Natural Killer Cell Mediated Cytotoxicity Pathway 83079!!Natural Killer Cell Mediated Cytotoxicity Pathway 490
ncbi summary :
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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