catalog number :
MBS421114
products full name :
Goat anti-ARPC2 Antibody
products short name :
ARPC2
products name syn :
ARPC2; actin related protein 2/3 complex; subunit 2; 34kDa; ARC34; PRO2446; p34-Arc; PNAS-139; ARP2/3 protein compex subunit 34; actin related protein 2/3 complex subunit 2; actin related protein 2/3 complex, subunit 2, 34kDa; ARC34; PRO2446; p34-Arc; PNAS-139; ARP2/3 protein compex subunit 34; actin related protein 2/3 complex subunit 2
other names :
actin-related protein 2/3 complex subunit 2; Actin-related protein 2/3 complex subunit 2; actin-related protein 2/3 complex subunit 2; arp2/3 complex 34 kDa subunit; ARP2/3 protein complex subunit 34; actin related protein 2/3 complex, subunit 2, 34kDa; Arp2/3 complex 34 kDa subunit; p34-ARC
products gene name :
ARPC2
other gene names :
ARPC2; ARPC2; ARC34; PRO2446; p34-Arc; PNAS-139; ARC34; p34-ARC
uniprot entry name :
ARPC2_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Spleen shows cytoplasm staining in some splenocytes in and around a T-cell area. Recommended concentration, 3-5ug/ml. Western Blot: Approx 33-34kDa band observed in Hela and Human Skeletal Muscle lysates (predicted MW of 34kDa according to NP_005722). Recommended for use at 0.1-0.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-EMKTITGKTFSSR, from the C Terminus of the protein sequence according to NP_005722.1; NP_690601.1. Corresponding Immunizing Peptide: Catalog #MBS426649
other info2 :
Important Note: The reported variants NP_005722.1 and NP_690601.1 represent identical protein.
products references :
Sakata D, Taniguchi H, Yasuda S, Adachi-Morishima A, Hamazaki Y, Nakayama R, Miki T, Minato N, Narumiya S.; Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1.; J Exp Med. 2007 Sep 3; 204(9):2031-8.; Pubmed 17682067
ncbi acc num :
NP_005722.1
ncbi gb acc num :
NM_005731.3
ncbi mol weight :
34,333 Da
ncbi pathways :
Axon Guidance Pathway 105688!!B Cell Receptor Signaling Pathway 198909!!Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!CDC42 Signaling Events Pathway 137994!!Developmental Biology Pathway 477129!!EPH-Ephrin Signaling Pathway 1016174!!EPHB-mediated Forward Signaling Pathway 1016176!!ErbB1 Downstream Signaling Pathway 138057!!Fc Gamma R-mediated Phagocytosis Pathway 114228
ncbi summary :
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]