Goat anti-FGFR1 Antibody | MyBioSource MBS421111 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-FGFR1 Antibody

catalog :

MBS421111

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, dog, cow

application :

western blot, immunohistochemistry, enzyme immunoassay

product information

catalog number :

MBS421111

products type :

Antibody

products full name :

Goat anti-FGFR1 Antibody

products short name :

FGFR1

products name syn :

FGFR1; H2; H3; H4; H5; CEK; FLG; FLT2; KAL2; BFGFR; C-FGR; N-SAM; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2; Pfeiffer syndrome); FLG protein; N-sam tyrosine kinase; tyrosylprotein kinase; protein-tyrosine kinase; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase-2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1; fibroblast growth factor receptor 1; CD331; FGFBR; FLJ99988; HBGFR; OGD; OTTHUMP00000190881; soluble FGFR1; soluble FGFR1 variant 2; FGFR1; H2; H3; H4; H5; CEK; FLG; FLT2; KAL2; BFGFR; C-FGR; N-SAM; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); FLG protein; N-sam tyrosine kinase; tyrosylprotein kinase; protein-tyrosine kinase; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase-2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1; fibroblast growth factor receptor 1; CD331; FGFBR; FLJ99988; HBGFR; OGD; OTTHUMP00000190881; soluble FGFR1 variant 1; soluble FGFR1 variant 2

other names :

fibroblast growth factor receptor 1 isoform 1; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1; FGFR1/PLAG1 fusion; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1; fibroblast growth factor receptor 1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; Proto-oncogene c-Fgr; CD_antigen: CD331

products gene name :

FGFR1

other gene names :

FGFR1; FGFR1; CEK; FLG; HH2; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; FGFR-1; BFGFR; bFGF-R-1; FLT-2

uniprot entry name :

FGFR1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human, Dog, Cow

sequence length :

822

sequence :

CLPRHPAQLANGGLKR

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Immunohistochemistry: In paraffin embedded Human Small Intestine shows staining of the enterocytic cytoplasm. Recommended concentration, 4-6ug/ml. Western Blot: Approx 75kDa band observed in human breast lysates (calculated MW of 82.2kDa according to NP_075593, 81.9kDa according to NP_075594). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

other info1 :

Epitope: C Terminus. Immunogen: Peptide with sequence CLPRHPAQLANGGLKR, from the C Terminus of the protein sequence according to NP_075598.2; NP_056934.2; NP_075593.1; NP_075594.1; NP_075599.1. Corresponding Immunizing Peptide: Catalog #MBS428099

other info2 :

Important Note: This antibody is expected to recognise five isoforms (as represented by NP_075598.2; NP_056934.2; NP_075593.1; NP_075594.1; NP_075599.1).

ncbi gi num :

105990522

ncbi acc num :

NP_075598.2

ncbi gb acc num :

NM_023110.2

ncbi mol weight :

95,344 Da

ncbi pathways :

Adaptive Immune System Pathway 366160!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Axon Guidance Pathway 105688!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Developmental Biology Pathway 477129!!Disease Pathway 530764!!Downstream Signal Transduction Pathway 106385

ncbi summary :

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

290 USD