catalog number :
MBS421102
products full name :
Goat anti-ELF5 Antibody
products short name :
ELF5
products name syn :
ELF5; E74-like factor 5 (ets domain transcription factor); ESE2; ESE-2; E74-like factor 5; epithelium-specific Ets transcription factor 2; ELF5; E74-like factor 5 (ets domain transcription factor); ESE2; ESE-2; E74-like factor 5; epithelium-specific Ets transcription factor 2
other names :
ETS-related transcription factor Elf-5 isoform 1; ETS-related transcription factor Elf-5; ETS-related transcription factor Elf-5; epithelium-restricted ESE-1-related Ets factor; epithelium-specific Ets transcription factor 2; E74-like factor 5 (ets domain transcription factor); E74-like factor 5; Epithelium-restricted ESE-1-related Ets factor; Epithelium-specific Ets transcription factor 2; ESE-2
products gene name :
ELF5
other gene names :
ELF5; ELF5; ESE2; ESE2; ESE-2
uniprot entry name :
ELF5_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Thyroid Gland shows nuclear staining in the epithelial cells of the glands. Data obtained from previous batch (different goat). Recommended concentration, 4-8ug/ml. Western Blot: Preliminary experiments in Human lysates of Lung, Kidney, Prostate and Testes gave no specific signal but low background (at antibody concentration up to 1ug/ml). Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-GKNAHGWQEDKL, from the C Terminus of the protein sequence according to NP_938195.1; NP_001413.1. Corresponding Immunizing Peptide: Catalog #MBS425323
other info2 :
Important Note: This antibody is expected to recognise both reported Human isoforms represented by NP_938195.1 and NP_001413.1.
ncbi acc num :
NP_938195.1
ncbi gb acc num :
NM_198381.1
ncbi mol weight :
18,866 Da
ncbi pathways :
Prolactin Signaling Pathway 814182!!Prolactin Signaling Pathway 814248
ncbi summary :
The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]