antibody

Goat anti-SSA1 / Ro52 Antibody

MBS421083

0.1 mg

290 USD

polyclonal

goat

nonconjugated

western blot, enzyme immunoassay

Antibody

Goat anti-SSA1 / Ro52 Antibody

SSA1/Ro52

TRIM21; tripartite motif-containing 21; RNF81; RO52; SSA; SSA1; 52kD Ro/SSA autoantigen; 52kDa ribonucleoprotein autoantigen SS-A/Ro; Sicca syndrome antigen A; Sjogren syndrome antigen A1 (52kD; ribonucleoprotein autoantigen SS-A/Ro); Sjogren syndrome antigen A1 (52kDa; ribonucleoprotein autoantigen SS-A/Ro); tripartite motif protein TRIM21; tripartite motif protein 21; TRIM21; tripartite motif-containing 21; RNF81, RO52, SSA, SSA1; 52kD Ro/SSA autoantigen; 52kDa ribonucleoprotein autoantigen SS-A/Ro; Sicca syndrome antigen A; Sjogren syndrome antigen A1 (52kD, ribonucleoprotein autoantigen SS-A/Ro); Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); tripartite motif protein TRIM21; tripartite motif protein 21

E3 ubiquitin-protein ligase TRIM21; E3 ubiquitin-protein ligase TRIM21; E3 ubiquitin-protein ligase TRIM21; SS-A; ro(SS-A); 52 kDa Ro protein; RING finger protein 81; Sicca syndrome antigen A; tripartite motif-containing 21; sjoegren syndrome type A antigen; tripartite motif-containing protein 21; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); tripartite motif containing 21; 52 kDa Ro protein; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; RING finger protein 81; Ro(SS-A); Sjoegren syndrome type A antigen; SS-A; Tripartite motif-containing protein 21

TRIM21

TRIM21; TRIM21; SSA; RO52; SSA1; RNF81; Ro/SSA; RNF81; RO52; SSA1; SS-A

RO52_HUMAN

Polyclonal

Goat

Human

475

CPLNIGSQGSTDY

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB-Trf)

Western Blot: In transfected HEK293 transiently expressing full-length Human TRIM21 (myc and DYKDDDDK tagged), a band of approx. 60kDa was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-myc tag antibody. Recommended concentration, 0.2-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.

Epitope: C Terminus. Immunogen: Peptide with sequence CPLNIGSQGSTDY, from the C Terminus of the protein sequence according to NP_003132.2.

Corresponding Immunizing Peptide: Catalog #MBS426814

15208660

NP_003132.2

NM_003141.3

45,057 Da

Adaptive Immune System Pathway 366160!!Antigen Processing: Ubiquitination Proteasome Degradation Pathway 366162!!Class I MHC Mediated Antigen Processing Presentation Pathway 366161!!Cytosolic Sensors Of Pathogen-associated DNA Pathway 576255!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Regulation Of Innate Immune Responses To Cytosolic DNA Pathway 833823!!STING Mediated Induction Of Host Immune Responses Pathway 685548!!Systemic Lupus Erythematosus Pathway 83122!!Systemic Lupus Erythematosus Pathway 534

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD