catalog number :
MBS421062
products full name :
Goat anti-JIP3 / Syd2 / JSAP1 Antibody
products short name :
JIP3/Syd2/JSAP1
products name syn :
MAPK8IP3; mitogen-activated protein kinase 8 interacting protein 3; JIP3; SYD2; JSAP1; FLJ00027; KIAA1066; JNK-interacting protein 3; JNK/SAPK-associated protein-1; similar to sperm specific protein; homolog of Drosophila Sunday driver 2; JNK/stress-activated protein kinase-associated protein 1; AC012180.8; DKFZp762N1113; C-jun-amino-terminal kinase interacting protein 3; homolog of Drosophila Sunday driver 2; MAPK8IP3; mitogen-activated protein kinase 8 interacting protein 3; JIP3; SYD2; JSAP1; FLJ00027; KIAA1066; JNK-interacting protein 3; JNK/SAPK-associated protein-1; similar to sperm specific protein; homolog of Drosophila Sunday driver 2; JNK/stress-activated protein kinase-associated protein 1; AC012180.8; DKFZp762N1113; C-jun-amino-terminal kinase interacting protein 3; homolog of Drosophila Sunday driver 2
other names :
C-Jun-amino-terminal kinase-interacting protein 3 isoform 1; C-Jun-amino-terminal kinase-interacting protein 3; C-Jun-amino-terminal kinase-interacting protein 3; JIP-3; JNK-interacting protein 3; JNK/SAPK-associated protein-1; JNK MAP kinase scaffold protein 3; homolog of Drosophila Sunday driver 2; C-jun-amino-terminal kinase interacting protein 3; JNK/stress-activated protein kinase-associated protein 1; mitogen-activated protein kinase 8-interacting protein 3; mitogen-activated protein kinase 8 interacting protein 3; JNK MAP kinase scaffold protein 3; Mitogen-activated protein kinase 8-interacting protein 3
products gene name :
MAPK8IP3
other gene names :
MAPK8IP3; MAPK8IP3; syd; JIP3; SYD2; JSAP1; JIP3; KIAA1066; JIP-3; JNK-interacting protein 3
uniprot entry name :
JIP3_HUMAN
reactivity :
Human, Mouse, Rat, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Mouse Brain shows axonal staining in various regions. Recommended concentration, 4-6ug/ml. Western Blot: No signal obtained yet but low background observed in Human Heart lysate at up to 2ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence MEIQMDEGGGVV-C, from the N Terminus of the protein sequence according to NP_055948.2; NP_001035529.1. Corresponding Immunizing Peptide: Catalog #MBS425241
other info2 :
Important Note: This antibody is expected to recognise both reported Human isoforms of this protein (as represented by NP_055948.2 and NP_001035529.1).
ncbi acc num :
NP_055948.2
ncbi gb acc num :
NM_015133.3
ncbi mol weight :
29,052 Da
ncbi pathways :
Arf6 Trafficking Events Pathway 137954!!MAPK Signaling Pathway 198779!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Signaling Events Mediated By Focal Adhesion Kinase Pathway 169348
ncbi summary :
The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]