product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-ACACB Antibody
catalog :
MBS421052
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS421052
products type :
Antibody
products full name :
Goat anti-ACACB Antibody
products short name :
ACACB
products name syn :
ACACB; acetyl-Coenzyme A carboxylase beta; ACCB; HACC275; acetyl-CoA carboxylase 2; Goat Anti-ACACB (mouse); acetyl-Coenzyme A carboxylase beta; ACCB; HACC275; acetyl-CoA carboxylase 2
other names :
acetyl-Coenzyme A carboxylase beta; Acetyl-CoA carboxylase 2; acetyl-CoA carboxylase 2; ACC-beta; acetyl-Coenzyme A carboxylase beta; acetyl-CoA carboxylase beta; ACC-betaIncluding the following 1 domains:Biotin carboxylase (EC:6.3.4.14)
products gene name :
ACACB
other gene names :
ACACB; ACACB; ACC2; ACCB; HACC275; ACC2; ACCB
uniprot entry name :
ACACB_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human
sequence length :
2458
sequence :
QLGEPDLSDKDRKD
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Preliminary experiments gave an approx 28kDa band in Human Heart lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 277kDa according to NP_001084.2. The 28kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:32000. Enzyme immunoassay: Sandwich-type ELISA with increasing amount of recombinant ACACB captured by a rabbit antibody. Recommended reporter concentration: 1-2ug/ml
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QLGEPDLSDKDRKD, from the internal region of the protein sequence according to NP_001084.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425499
ncbi gi num :
61743950
ncbi acc num :
NP_001084.2
ncbi gb acc num :
NM_001093.2
ncbi mol weight :
255,093 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Activation Of Gene Expression By SREBF (SREBP) Pathway 685552!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!BDNF Signaling Pathway 712093!!Biotin Transport And Metabolism Pathway 106257!!ChREBP Activates Metabolic Gene Expression Pathway 106104!!Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway 906000
ncbi summary :
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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