Goat anti-PPAR delta (Isoform 1) Antibody | MyBioSource MBS421047 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-PPAR delta (Isoform 1) Antibody

catalog :

MBS421047

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS421047

products type :

Antibody

products full name :

Goat anti-PPAR delta (Isoform 1) Antibody

products short name :

PPAR delta

products name syn :

PPARD; FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB; MGC3931; PPAR-beta; peroxisome proliferative activated receptor, delta; nuclear hormone receptor 1; peroxisome proliferative activated receptor delta; OTTHUMP00000016256; OTTHUMP00000016257; PPARD antibody; FAAR antibody; NUC1 antibody; NUCI antibody; NR1C2 antibody; NUCII antibody; PPARB antibody; MGC3931 antibody; PPAR-beta antibody; peroxisome proliferative activated receptor; delta antibody; nuclear hormone receptor 1 antibody; peroxisome proliferator-activated receptor delta antibody; OTTHUMP00000016256 antibody; OTTHUMP00000016257 antibody; PPAR delta (Isoform 1)

other names :

peroxisome proliferator-activated receptor delta isoform 1; Peroxisome proliferator-activated receptor delta; peroxisome proliferator-activated receptor delta; peroxisome proliferator activated receptor delta; NUCI; Nuclear hormone receptor 1; NUC1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; PPAR-beta

products gene name :

PPARD

products gene name syn :

PPAR delta

other gene names :

PPARD; PPARD; FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB; NR1C2; PPARB; PPAR-delta; NUC1; PPAR-beta

uniprot entry name :

PPARD_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Rat; Expected from sequence similarity: Human, Mouse, Rat, Pig, Cow

sequence length :

441

sequence :

CHPLLQEIYKDMY

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 55kDa band observed in Human Lymphoblastoid and T cell line MOLT4 lysates (calculated MW of 49.9kDa according to NP_006229.1). Recommended concentration: 1-3ug/ml.

other info1 :

Immunogen: Peptide with sequence CHPLLQEIYKDMY, from the C Terminus of the protein sequence according to NP_006229.1. Epitope: C Terminus

other info2 :

Note: This antibody is expected to recognise isoform 1 (NP_006229) of PPAR delta, but not isoform 2, a shorter protein (NP_803184) with a different C-terminus.

ncbi gi num :

5453940

ncbi acc num :

NP_006229.1

ncbi gb acc num :

NM_006238.4

ncbi mol weight :

38,855 Da

ncbi pathways :

Acute Myeloid Leukemia Pathway (83117); Acute Myeloid Leukemia Pathway (529); Adipogenesis Pathway (198832); Energy Metabolism Pathway (198907); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (1270010); Gene Expression Pathway (1269649); Generic Transcription Pathway (1269650); Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway (1270014); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001)

ncbi summary :

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage