product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-WNT3 Antibody
catalog :
MBS421042
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS421042
products type :
Antibody
products full name :
Goat anti-WNT3 Antibody
products short name :
WNT3
products name syn :
WNT3; wingless-type MMTV integration site family; member 3; INT4; MGC131950; MGC138321; MGC138323; WNT-3 proto-oncogene protein precursor; WNT3; wingless-type MMTV integration site family, member 3; INT4; MGC131950; MGC138321; MGC138323; WNT-3 proto-oncogene protein precursor
other names :
proto-oncogene Wnt-3; Proto-oncogene Wnt-3; proto-oncogene Wnt-3; WNT-3 proto-oncogene protein; proto-oncogene Int-4 homolog; wingless-type MMTV integration site family, member 3; Proto-oncogene Int-4 homolog
products gene name :
WNT3
other gene names :
WNT3; WNT3; INT4; INT4
uniprot entry name :
WNT3_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog
sequence length :
355
sequence :
CGRGHNTRTEKRKEK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
app notes :
Immunohistochemistry: In paraffin embedded Human Breast shows cytoplasm staining in some luminal epithelial cells. Recommended concentration, 2-4ug/ml. Western Blot: Approx 40kDa band observed in lysates of cell line HEK293 (calculated MW of 39.6kDa according to NP_110380.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000. Immunocytochemsitry/Immunofluorescence This antibody has been successfully used in ICC/IF for mouse hippocampal primary astrocytes as described in the following paper: Okamoto et al, FASEB J. 2011 Jul 11; PMID: 21746862.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence CGRGHNTRTEKRKEK, from the internal region of the protein sequence according to NP_110380.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425179
ncbi gi num :
13540477
ncbi acc num :
NP_110380.1
ncbi gb acc num :
NM_030753.4
ncbi mol weight :
39,645 Da
ncbi pathways :
Basal Cell Carcinoma Pathway 83113!!Basal Cell Carcinoma Pathway 525!!Class B/2 (Secretin Family Receptors) Pathway 106378!!DNA Damage Response (only ATM Dependent) Pathway 198827!!Disease Pathway 530764!!GPCR Ligand Binding Pathway 161020!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Hedgehog Signaling Pathway 83063!!Hedgehog Signaling Pathway 474
ncbi summary :
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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