antibody

Goat anti-PAX5/BSAP Antibody

MBS421040

0.1 mg

300 USD

polyclonal

goat

nonconjugated

human, mouse

western blot, enzyme immunoassay

Antibody

Goat anti-PAX5/BSAP Antibody

PAX5/BSAP

PAX5; BSAP; paired box gene 5 (B-cell lineage specific activator protein); B-cell lineage specific activator protein; paired box homeotic gene 5 (B-cell lineage specific activator protein); paired box 5; B cell specific activator protein; B-cell lineage s; PAX5 antibody; BSAP antibody; paired box gene 5 (B-cell lineage specific activator protein) antibody; B-cell lineage specific activator protein antibody; paired box homeotic gene 5 (B-cell lineage specific activator protein) antibody; paired box 5 antibody; B cell specific activator protein antibody; B-cell lineage specific activator antibody; paired box homeotic gene 5 antibody; transcription factor PAX 5 antibody; PAX5 / BSAP

paired box protein Pax-5 isoform 1; Paired box protein Pax-5; paired box protein Pax-5; paired box 5; B-cell-specific transcription factor; BSAP

PAX5

BSAP

PAX5; PAX5; ALL3; BSAP; BSAP

PAX5_HUMAN

Polyclonal

Goat

Tested: Human; Expected from sequence similarity: Human, Mouse

391

DLEKNYPTPRTSR

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Approx 40kDa band observed in Human Lymph and Human Spleen lysates (calculated MW of 42.1kDa according to NP_057953.1). Recommended concentration: 0.3-1ug/ml.

Immunogen: Peptide with sequence DLEKNYPTPRTSR-C, from the N Terminus of the protein sequence according to NP_057953.1. Epitope: N Terminus

9951920

NP_057953.1

NM_016734.2

34,132 Da

C-MYB Transcription Factor Network Pathway (138073); Id Signaling Pathway (198871); Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)

This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

0.1 mg

300 USD