Goat anti-Smooth muscle alpha-actin Antibody | MyBioSource MBS421038 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-Smooth muscle alpha-actin Antibody

catalog :

MBS421038

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog

application :

western blot, immunohistochemistry, immunocytochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS421038

products type :

Antibody

products full name :

Goat anti-Smooth muscle alpha-actin Antibody

products short name :

Smooth muscle alpha-actin

products name syn :

ACTA2; actin, alpha 2, smooth muscle, aorta; OTTHUMP00000020042; ACTSA; AAT6; ACTSA; alpha 2 actin; alpha-cardiac actin; growth-inhibiting gene 46; smooth muscle alpha-actin; actin; alpha 2; smooth muscle; aorta antibody; OTTHUMP00000020042 antibody; ACTA2 antibody; ACTSA antibody; AAT6 antibody; ACTSA antibody; alpha 2 actin antibody; alpha-cardiac actin antibody; growth-inhibiting gene 4 antibody; smooth muscle alpha-actin antibody; Smooth muscle alpha-actin; Smooth muscle alpha-actin

other names :

actin, aortic smooth muscle; Actin, aortic smooth muscle; actin, aortic smooth muscle; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein

products gene name :

ACTA2

other gene names :

ACTA2; ACTA2; AAT6; ACTSA; MYMY5; ACTSA; ACTVS

uniprot entry name :

ACTA_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Mouse, Rat, Pig; Expected from sequence similarity: Human, Mouse, Rat, Dog

sequence length :

377

sequence :

EEEDSTALVC

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 2000. Immunohistochemistry: In paraffin embedded Human and Murine Lung shows staining of the alveolar walls. Recommended concentration, 2-4ug/ml. Data obtained from a different batch (different goat). Western Blot: Approx 40-45kDa band observed in Human Duodenum, Heart and Skeletal Muscle lysates (calculated MW of 42. 0kDa according to NP_001604.1). Recommended concentration: 0.3-1ug/ml.

other info1 :

Immunogen: Peptide with sequence EEEDSTALVC, from the N Terminus of the protein sequence according to NP_001604.1; NP_001135417.1. Epitope: N Terminus

other info2 :

Note: Variants NP_001604.1 and NP_001135417.1 encode the same protein.

ncbi gi num :

4501883

ncbi acc num :

NP_001604.1

ncbi gb acc num :

NM_001613.2

ncbi mol weight :

42,009 Da

ncbi pathways :

Muscle Contraction Pathway (1269868); Myometrial Relaxation And Contraction Pathways (198759); Smooth Muscle Contraction Pathway (1269870); Striated Muscle Contraction Pathway (198903); Vascular Smooth Muscle Contraction Pathway (96530); Vascular Smooth Muscle Contraction Pathway (96866)

ncbi summary :

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

uniprot summary :

ACTA2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the actin family. Protein type: Cytoskeletal; Contractile; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 10q23.3. Cellular Component: actin cytoskeleton; cytoplasm; cytosol; extracellular space; filopodium; lamellipodium; protein complex; smooth muscle contractile fiber. Molecular Function: ATP binding; protein kinase binding. Biological Process: muscle contraction; regulation of blood pressure; response to virus; vascular smooth muscle contraction. Disease: Aortic Aneurysm, Familial Thoracic 6; Moyamoya Disease 5; Multisystemic Smooth Muscle Dysfunction Syndrome

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage