product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-SEC61A1 Antibody
catalog :
MBS421035
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, dog, cow
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421035
products type :
Antibody
products full name :
Goat anti-SEC61A1 Antibody
products short name :
SEC61A1
products name syn :
SEC61A1; HSEC61; SEC61; SEC61A; protein transport protein SEC61 alpha subunit isoform 1; sec61 homolog; Sec61 alpha 1 subunit (S. cerevisiae); Sec61 alpha 1 subunit; Sec61 alpha-1; SEC61A1 antibody; HSEC61 antibody; SEC61 antibody; SEC61A antibody; protein transport protein SEC61 alpha subunit isoform 1 antibody; sec61 homolog antibody; Sec61 alpha 1 subunit (S. cerevisiae) antibody; Sec61 alpha 1 subunit antibody; Sec61 alpha-1 antibody
other names :
protein transport protein Sec61 subunit alpha isoform 1; Protein transport protein Sec61 subunit alpha isoform 1; protein transport protein Sec61 subunit alpha isoform 1; Sec61 translocon alpha 1 subunit
products gene name :
SEC61A1
other gene names :
SEC61A1; SEC61A1; SEC61; HSEC61; SEC61A; SEC61A; Sec61 alpha-1
uniprot entry name :
S61A1_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human, Mouse; Expected from sequence similarity: Human, Dog, Cow, Pig
sequence length :
476
sequence :
KEQSEVGSMGALLF
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Approx 48kDa band observed in Human Brain (Cerebelum) lysates (calculated MW of 52.3kDa according to NP_037468.1). Recommended concentration: 0.3-1ug/ml.
other info1 :
Immunogen: Peptide with sequence C-KEQSEVGSMGALLF, from the C Terminus of the protein sequence according to NP_037468.1. Epitope: C Terminus
ncbi gi num :
7019415
ncbi acc num :
NP_037468.1
ncbi gb acc num :
NM_013336.3
ncbi mol weight :
38,849 Da
ncbi pathways :
Adaptive Immune System Pathway (1269171); Antigen Processing-Cross Presentation Pathway (1269195); Class I MHC Mediated Antigen Processing Presentation Pathway (1269192); ER-Phagosome Pathway (1269197); Gene Expression Pathway (1269649); IRE1alpha Activates Chaperones Pathway (1268759); Immune System Pathway (1269170); Metabolism Of Proteins Pathway (1268677); Phagosome Pathway (153910); Phagosome Pathway (153859)
ncbi summary :
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]
uniprot summary :
SEC61A1: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins. Belongs to the SecY/SEC61-alpha family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Endoplasmic reticulum; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 3q21.3. Cellular Component: cytosol; integral to endoplasmic reticulum membrane; membrane; rough endoplasmic reticulum. Molecular Function: protein binding; ribosome binding. Biological Process: cell growth; endoplasmic reticulum organization and biogenesis; posttranslational protein targeting to membrane; protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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