catalog number :
MBS421015
products full name :
Goat anti-D-amino-acid oxidase Antibody
products short name :
D-amino-acid oxidase
products name syn :
DAO; D-amino-acid oxidase; DAAO; DAMOX; MGC35381; OXDA; Goat Anti-D-amino-acid oxidase (aa286-298); DAO; D-amino-acid oxidase; DAAO; DAMOX; MGC35381; OXDA
other names :
D-amino-acid oxidase; D-amino-acid oxidase; D-amino-acid oxidase; D-amino acid oxidase; D-amino-acid oxidase
other gene names :
DAO; DAO; DAAO; OXDA; DAMOX; DAMOX; DAAO; DAMOX; DAO
uniprot entry name :
OXDA_HUMAN
reactivity :
Human, Rat, Mouse
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments in human brain (cerebellum, hippocampus, substantia nigra) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-EEKKLSRMPPSH, from the C Terminus of the protein sequence according to NP_001908.3.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428051
ncbi acc num :
NP_001908.3
ncbi gb acc num :
NM_001917.4
ncbi mol weight :
39,474 Da
ncbi pathways :
Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!D-Arginine And D-ornithine Metabolism Pathway 82972!!D-Arginine And D-ornithine Metabolism Pathway 341!!Glycine, Serine And Threonine Metabolism Pathway 82949!!Glycine, Serine And Threonine Metabolism Pathway 313!!Glyoxylate Metabolism Pathway 160990!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169
ncbi summary :
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]