catalog number :
MBS421012
products full name :
Goat anti-MAX Antibody
products short name :
MAX
products name syn :
MAX; MAX protein; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; myc-associated factor X; helix-loop-helix zipper protein; MYC associated factor X; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; orf1; MAX; MAX protein; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; myc-associated factor X; helix-loop-helix zipper protein; MYC associated factor X; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; orf1
other names :
protein max isoform a; Protein max; protein max; class D basic helix-loop-helix protein 4; MYC associated factor X; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X
other gene names :
MAX; MAX; bHLHd4; BHLHD4; bHLHd4
uniprot entry name :
MAX_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
EEPQSRKKLRMEAS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 22kDa band observed in lysates of cell line Jurkat and of Mouse and Rat Spleen lysates (calculated MW of 18.3kDa according to NP_002373.3). Recommended for use at 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-EEPQSRKKLRMEAS, from the C Terminus of the protein sequence according to NP_002373.3; NP_660087.1. Corresponding Immunizing Peptide: Catalog #MBS425418
other info2 :
Important Note: This antibody is expected to recognize both reported isoforms (NP_002373.3; NP_660087.1).
ncbi acc num :
NP_002373.3
ncbi gb acc num :
NM_002382.4
ncbi mol weight :
9,599 Da
ncbi pathways :
C-MYC Pathway 169344!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Cyclin A:Cdk2-associated Events At S Phase Entry Pathway 105783!!Cyclin E Associated Events During G1/S Transition Pathway 105770!!G1/S Transition Pathway 105769!!Integrated Breast Cancer Pathway 219801!!MAPK Signaling Pathway 198779!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456
ncbi summary :
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]