Goat anti-MIF Antibody | MyBioSource MBS420999 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-MIF Antibody

catalog :

MBS420999

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420999

products type :

Antibody

products full name :

Goat anti-MIF Antibody

products short name :

MIF

products name syn :

Goat Anti-MIF, Biotinylated Antibody; MIF; macrophage migration inhibitory factor (glycosylation-inhibiting factor); HGNC: 7097; GIF; GLIF; MMIF; glycosylation-inhibiting factor; phenylpyruvate tautomerase; macrophage migration inhibitory factor; MIF antibody; macrophage migration inhibitory factor (glycosylation-inhibiting factor) antibody; HGNC: 7097 antibody; GIF antibody; GLIF antibody; MMIF antibody; glycosylation-inhibiting factor antibody; phenylpyruvate tautomerase antibody; macrophage migration inhibitory factor antibody

other names :

macrophage migration inhibitory factor; Macrophage migration inhibitory factor; macrophage migration inhibitory factor; macrophage migration inhibitory factor (glycosylation-inhibiting factor); Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase (EC:5.3.3.12); Phenylpyruvate tautomerase

products gene name :

MIF

other gene names :

MIF; MIF; GIF; GLIF; MMIF; GLIF; MMIF; MIF; GIF

uniprot entry name :

MIF_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human, Rat, Mouse

sequence length :

115

sequence :

NAANVGWNNSTFA

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), ELISA (EIA)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 13kDa band observed in Human Lymph Node, and Thymus lysates and similar bands are observed in lysates of cell lines Daudi and Jurkat (calculated MW of 12.5kDa according to NP_002406.1). Recommended concentration: 0.01-0.03ug/ml. Enzyme immunoassay: Sandwich-type ELISA with increasing amount of recombinant MIF captured by a rabbit antibody. Recommended reporter concentration: 1.5-3ug/ml.

other info1 :

Immunogen: Peptide with sequence C-NAANVGWNNSTFA, from the C Terminus of the protein sequence according to NP_002406.1. Epitope: C Terminus

ncbi gi num :

4505185

ncbi acc num :

NP_002406.1

ncbi gb acc num :

NM_002415.1

ncbi mol weight :

12,476 Da

ncbi pathways :

Adipogenesis Pathway (198832); Cell Surface Interactions At The Vascular Wall Pathway (1269373); Hemostasis Pathway (1269340); Phenylalanine Metabolism Pathway (82960); Phenylalanine Metabolism Pathway (327); Spinal Cord Injury Pathway (739007); Tyrosine Metabolism Pathway (82959); Tyrosine Metabolism Pathway (325)

ncbi summary :

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]

uniprot summary :

MIF: a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. Also acts as a phenylpyruvate tautomerase. Protein type: Amino Acid Metabolism - tyrosine; Cytokine; Cell development/differentiation; EC 5.3.3.12; EC 5.3.2.1; Isomerase; Apoptosis; Amino Acid Metabolism - phenylalanine. Chromosomal Location of Human Ortholog: 22q11.23. Cellular Component: cell surface; cytoplasm; extracellular region; extracellular space; myelin sheath; nucleoplasm; vesicle. Molecular Function: chemoattractant activity; cytokine activity; dopachrome isomerase activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; phenylpyruvate tautomerase activity; protein binding; receptor binding. Biological Process: carboxylic acid metabolic process; cell aging; cell proliferation; cell surface receptor linked signal transduction; DNA damage response, signal transduction by p53 class mediator; inflammatory response; innate immune response; leukocyte migration; negative regulation of apoptosis; negative regulation of cellular protein metabolic process; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of mature B cell apoptosis; negative regulation of myeloid cell apoptosis; positive chemotaxis; positive regulation of B cell proliferation; positive regulation of cytokine secretion; positive regulation of fibroblast proliferation; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of MAP kinase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphorylation; prostaglandin biosynthetic process; regulation of macrophage activation. Disease: Rheumatoid Arthritis, Systemic Juvenile

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage