Goat anti-GTF2IRD1 Antibody | MyBioSource MBS420989 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-GTF2IRD1 Antibody

catalog :

MBS420989

quantity :

0.1 mg

price :

225 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog

application :

enzyme immunoassay

product information

catalog number :

MBS420989

products type :

Antibody

products full name :

Goat anti-GTF2IRD1 Antibody

products short name :

GTF2IRD1

products name syn :

GTF2IRD1; GTF2I repeat domain containing 1; HGNC:4661; CREAM1; GTF3; MUSTRD1; RBAP2; WBSCR11; WBSCR12; hMusTRD1alpha1; GTF2I repeat domain-containing 1; Williams-Beuren syndrome chromosome region 11; general transcription factor 3; muscle TFII-I repeat; GTF2IRD1; GTF2I repeat domain containing 1; HGNC:4661; CREAM1; GTF3; MUSTRD1; RBAP2; WBSCR11; WBSCR12; hMusTRD1alpha1; GTF2I repeat domain-containing 1; Williams-Beuren syndrome chromosome region 11; general transcription factor 3; muscle TFII-I repeat

other names :

general transcription factor II-I repeat domain-containing protein 1 isoform 1; General transcription factor II-I repeat domain-containing protein 1; general transcription factor II-I repeat domain-containing protein 1; USE B1-binding protein; general transcription factor 3; general transcription factor III; binding factor for early enhancer; slow-muscle-fiber enhancer-binding protein; Williams-Beuren syndrome chromosome region 11; williams-Beuren syndrome chromosomal region 12 protein; muscle TFII-I repeat domain-containing protein 1 alpha 1; GTF2I repeat domain containing 1; General transcription factor III; MusTRD1/BEN; Muscle TFII-I repeat domain-containing protein 1; Slow-muscle-fiber enhancer-binding protein; USE B1-binding protein; Williams-Beuren syndrome chromosomal region 11 protein; Williams-Beuren syndrome chromosomal region 12 protein

products gene name :

GTF2IRD1

other gene names :

GTF2IRD1; GTF2IRD1; BEN; WBS; GTF3; RBAP2; CREAM1; MUSTRD1; WBSCR11; WBSCR12; hMusTRD1alpha1; CREAM1; GTF3; MUSTRD1; RBAP2; WBSCR11; WBSCR12; GTF2I repeat domain-containing protein 1

uniprot entry name :

GT2D1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human, Mouse, Rat, Dog

sequence length :

959

sequence :

NKFTKDTTKLEPAS

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA)

app notes :

Western Blot: Preliminary experiments gave bands at approx 30kDa and 40kDa in Human Heart lysate after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 106kDa according to NP_057412.1 and NP_005676.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). Peptide ELISA: antibody detection limit dilution 1:64000.

other info1 :

Epitope: Internal Region. Immunogen: Peptide with sequence C-NKFTKDTTKLEPAS, from the internal region of the protein sequence according to NP_057412.1; NP_005676.2. Corresponding Immunizing Peptide: Catalog #MBS426742

other info2 :

Important Note: This antibody is expected to recognise both reported isoforms (NP_057412.1 and NP_005676.2).

ncbi gi num :

7705387

ncbi acc num :

NP_057412.1

ncbi gb acc num :

NM_016328.2

ncbi mol weight :

107,979 Da

ncbi pathways :

Basal Transcription Factors Pathway 83038!!Basal Transcription Factors Pathway 443!!Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865!!CGMP-PKG Signaling Pathway 983748!!CGMP-PKG Signaling Pathway 985584

ncbi summary :

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

size :

0.1 mg

price :

225 USD