Goat anti-ALDH1A1 (C Terminus) Antibody | MyBioSource MBS420981 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-ALDH1A1 (C Terminus) Antibody

catalog :

MBS420981

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420981

products type :

Antibody

products full name :

Goat anti-ALDH1A1 (C Terminus) Antibody

products short name :

ALDH1A1

products name syn :

Goat Anti-ALDH1A1 (Internal) Antibody; ALDH1A1; aldehyde dehydrogenase 1 family, member A1; ALDC; ALDH-E1; ALDH1; ALDH11; MGC2318,; PUMB1; RALDH1; ALDH class 1; acetaldehyde dehydrogenase 1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase 1A1; aldehyde dehydrogenase, liver cytosolic; ALDH1A1 antibody; aldehyde dehydrogenase 1 family; member A1 antibody; ALDC antibody; ALDH-E1 antibody; ALDH1 antibody; ALDH11 antibody; MGC2318; antibody; PUMB1 antibody; RALDH1 antibody; ALDH class 1 antibody; acetaldehyde dehydrogenase 1 antibody; aldehyde dehydrogenase 1; soluble antibody; aldehyde dehydrogenase 1A1 antibody; aldehyde dehydrogenase; liver cytosolic antibody; retinal dehydrogenase 1 antibody; retinaldehyde dehydrogenase 1 antibody; ALDH1A1 (C Terminus)

other names :

retinal dehydrogenase 1; Retinal dehydrogenase 1; retinal dehydrogenase 1; aldehyde dehydrogenase 1 family member A1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic

products gene name :

ALDH1A1

other gene names :

ALDH1A1; ALDH1A1; ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e; ALDC; ALDH1; PUMB1; RALDH 1; RalDH1

uniprot entry name :

AL1A1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow

sequence length :

501

sequence :

EVKTVTVKISQKNS

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 16000. Immunohistochemistry: This antibody has been successfully used in IHC on mouse Peyer's patches as described in the following paper: Iwata et al, Immunity.2004 Oct;21(4): 527-38.; PMID: 15485630. Western Blot: Approx 55kDa band observed in Human and Mouse Liver, and Rat Testis lysates (calculated MW of 54.5kDa according to Human NP_000680.2; Mouse NP_038495.2 and Rat NP_071852.2). Recommended concentration: 0.1-0.3ug/ml.

other info1 :

Immunogen: Peptide with sequence C-EVKTVTVKISQKNS, from the C Terminus of the protein sequence according to NP_000680.2. Epitope: C Terminus

other info2 :

Note: This antibody may cross-react with ALDH1A2 (GeneID 8854) with one residue difference from this design and with ALDH2 (GeneID 217) with two residues difference from this design.

ncbi gi num :

21361176

ncbi acc num :

NP_000680.2

ncbi gb acc num :

NM_000689.4

ncbi mol weight :

54,862 Da

ncbi pathways :

Biological Oxidations Pathway (1270189); Ethanol Oxidation Pathway (1270206); Fatty Acid Omega Oxidation Pathway (198915); Folate-Alcohol And Cancer Pathway (920980); Fructose Catabolism Pathway (1269967); Fructose Metabolism Pathway (1269965); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Carbohydrates Pathway (1269957); Phase 1 - Functionalization Of Compounds Pathway (1270190)

ncbi summary :

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]

uniprot summary :

ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. Protein type: Oxidoreductase; Cofactor and Vitamin Metabolism - retinol; Apoptosis; EC 1.2.1.36; GAPs; GAPs, Ras. Chromosomal Location of Human Ortholog: 9q21.13. Cellular Component: cytoplasm; cytosol. Molecular Function: aldehyde dehydrogenase (NAD) activity; androgen binding; benzaldehyde dehydrogenase (NAD+) activity; GTPase activator activity; retinal dehydrogenase activity. Biological Process: aldehyde metabolic process; ethanol oxidation; positive regulation of GTPase activity; retinol metabolic process

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage