catalog number :
MBS420975
products full name :
Goat anti-AOC3 Antibody
products short name :
AOC3
products name syn :
AOC3; amine oxidase; copper containing 3 (vascular adhesion protein 1); HPAO; SSAO; VAP-1; VAP1; amine oxidase; copper containing 3; copper amine oxidase; semicarbazide-sensitive amine oxidase; vascular adhesion protein 1; Goat Anti-AOC3 / VAP1; amine oxidase, copper containing 3 (vascular adhesion protein 1); HPAO; SSAO; VAP-1; VAP1; amine oxidase, copper containing 3; copper amine oxidase; semicarbazide-sensitive amine oxidase; vascular adhesion protein 1
other names :
membrane primary amine oxidase isoform 1; Membrane primary amine oxidase; membrane primary amine oxidase; copper amine oxidase; placenta copper monamine oxidase; semicarbazide-sensitive amine oxidase; amine oxidase, copper containing 3 (vascular adhesion protein 1); amine oxidase, copper containing 3; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1
products gene name :
AOC3
other gene names :
AOC3; AOC3; HPAO; SSAO; VAP1; VAP-1; VAP1; SSAO; VAP-1
uniprot entry name :
AOC3_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Liver shows membranous staining in sinusoid lining cells surrounding hepatocytes. Recommended concentration, 3-5ug/ml. Western Blot: Preliminary experiments gave an approx 55kDa band in Human Adipose and Lung lysates after 0.01ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 84.6kDa according to NP_003725.1. The 55kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region (Near the C Terminus). Immunogen: Peptide with sequence C-DEDPSFYSADSIY, from the internal region (near the C Terminus) of the protein sequence according to NP_003725.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425580
ncbi acc num :
NP_003725.1
ncbi gb acc num :
NM_003734.3
ncbi mol weight :
24,533 Da
ncbi pathways :
Glycine, Serine And Threonine Metabolism Pathway 82949!!Glycine, Serine And Threonine Metabolism Pathway 313!!Metabolic Pathways 132956!!Phenylalanine Metabolism Pathway 82960!!Phenylalanine Metabolism Pathway 327!!Tyrosine Metabolism Pathway 82959!!Tyrosine Metabolism Pathway 325!!Beta-Alanine Metabolism Pathway 82966!!Beta-Alanine Metabolism Pathway 335!!Phenylethylamine Degradation I Pathway 547500
ncbi summary :
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]