catalog number :
MBS420969
products full name :
Goat anti-ZCCHC11/PAPD3 Antibody
products short name :
ZCCHC11/PAPD3
products name syn :
ZCCHC11; KIAA0191; zinc finger, CCHC domain containing 11; PAPD3; PAP associated domain containing 3; ZCCHC11 antibody; KIAA0191 antibody; zinc finger; CCHC domain containing 11 antibody; PAPD3 antibody; PAP associated domain containing 3 antibody; ZCCHC11 / PAPD3
other names :
terminal uridylyltransferase 4 isoform a; Terminal uridylyltransferase 4; terminal uridylyltransferase 4; zinc finger CCHC-type containing 11; Zinc finger CCHC domain-containing protein 11
products gene name :
ZCCHC11
products gene name syn :
PAPD3
other gene names :
ZCCHC11; ZCCHC11; TUT4; PAPD3; KIAA0191; TUT4; TUTase 4
uniprot entry name :
TUT4_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
sequence :
RERCPHPPRGNVSE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Immunohistochemistry: In paraffin embedded Human Lymph Node shows nuclear staining of select lymphocytes and staining of macrophages. Recommended concentration, 2-6ug/ml.
other info1 :
Immunogen: Peptide with sequence RERCPHPPRGNVSE, from the C Terminus of the protein sequence according to NP_001009881.1; NP_056084.1; NP_001009882.1. Epitope: C Terminus
other info2 :
Note: This antibody is expected to recognize all 3 reported isoforms (as represented by NP_001009881.1; NP_056084.1; NP_001009882.1)
ncbi acc num :
NP_001009881.1
ncbi gb acc num :
NM_001009881.2
ncbi mol weight :
81,141 Da
ncbi summary :
ZCCHC11 is an RNA uridyltransferase (EC 2.7.7.52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al., 2009 [PubMed 19701194]).[supplied by OMIM, Jan 2011]
uniprot summary :
ZCCHC11: a zinc finger protein that may participate in toll-receptor signaling by suppressing TRAF6-dependent activation of NF-kappaB. Two alternatively spliced isoforms have been reported. Protein type: Transferase; EC 2.7.7.52; Cell development/differentiation; RNA processing. Chromosomal Location of Human Ortholog: 1p32.3. Cellular Component: cytoplasm; extracellular space; nucleolus. Molecular Function: protein binding; RNA uridylyltransferase activity; zinc ion binding. Biological Process: pre-microRNA processing; RNA 3'-end processing; stem cell maintenance