catalog number : 
MBS420961
products full name : 
Goat anti-SMO (internal) Antibody
products short name : 
SMO
products name syn : 
SMO; smoothened homolog (Drosophila); Gx; SMOH; seven transmembrane helix receptor; smoothened; Goat Anti-SMO (C Terminus); SMO; smoothened homolog (Drosophila); Gx; SMOH; seven transmembrane helix receptor; smoothened
other names : 
smoothened homolog; Smoothened homolog; smoothened homolog; protein Gx; frizzled family member 11; seven transmembrane helix receptor; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor; smoothened, frizzled class receptor; Protein Gx
other gene names : 
SMO; SMO; Gx; SMOH; FZD11; SMOH; SMO
uniprot entry name : 
SMO_HUMAN
reactivity : 
Human, Mouse, Rat, Dog, Zebrafish
purity : 
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form : 
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration : 
100ug specific antibody in 200ul
storage stability : 
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application : 
Peptide ELISA (EIA), Western Blot (WB)
app notes : 
Western Blot: Approx 60kDa band observed in Human Bone Marrow lysates (calculated MW of 86.4kDa according to NP_005622.1). The observed molecular weight corresponds to findings. A product of different design reacting to a different part of the same protein. Recommended concentration: 0.1-0.3ug/ml.  Peptide ELISA: antibody detection limit dilution 1:1000.
other info1 : 
Epitope: Internal Region.  Immunogen: Peptide with sequence C-QSDDEPKRIKKS, from the internal region of the protein sequence according to NP_005622.1.
other info2 : 
Corresponding Immunizing Peptide:  Catalog #MBS426743
ncbi acc num : 
NP_005622.1
ncbi gb acc num : 
NM_005631.4
ncbi mol weight : 
86,397 Da
ncbi pathways : 
Basal Cell Carcinoma Pathway  83113!!Basal Cell Carcinoma Pathway  525!!Class B/2 (Secretin Family Receptors) Pathway  106378!!GPCR Ligand Binding Pathway  161020!!GPCRs, Other Pathway  198765!!Hedgehog Signaling Pathway  198835!!Hedgehog Signaling Events Mediated By Gli Proteins Pathway  137912!!Hedgehog Signaling Pathway  83063!!Hedgehog Signaling Pathway  474!!Integrated Pancreatic Cancer Pathway  711360
ncbi summary : 
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]