catalog number :
MBS420959
products full name :
Goat anti-FACL4 / ACSL4 Antibody
products short name :
FACL4/ACSL4
products name syn :
ACSL4; acyl-CoA synthetase long-chain family member 4; FACL4; fatty-acid-Coenzyme A ligase; long-chain 4; ACS4; LACS 4; lignoceroyl-CoA synthase; Fatty acid coenzyme A ligase; long-chain 4; MRX63; LACS4; MRX68; acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; acyl-CoA synthetase long-chain family member 4; FACL4; fatty-acid-Coenzyme A ligase, long-chain 4; ACS4; LACS 4; lignoceroyl-CoA synthase; Fatty acid coenzyme A ligase, long-chain 4; MRX63; LACS4; MRX68; acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4
other names :
long-chain-fatty-acid--CoA ligase 4 isoform 1; Long-chain-fatty-acid--CoA ligase 4; long-chain-fatty-acid--CoA ligase 4; LACS 4; acyl-CoA synthetase 4; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; fatty-acid-Coenzyme A ligase, long-chain 4; acyl-CoA synthetase long-chain family member 4; Long-chain acyl-CoA synthetase 4; LACS 4
products gene name :
ACSL4
other gene names :
ACSL4; ACSL4; ACS4; FACL4; LACS4; MRX63; MRX68; ACS4; FACL4; LACS4; LACS 4
uniprot entry name :
ACSL4_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 80kDa band observed in lysates of cell line HepG2 (calculated MW of 79.2kDa according to NP_075266.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-HYLKDIERMYGGK, from the C Terminus of the protein sequence according to NP_004449.1; NP_075266.1. Corresponding Immunizing Peptide: Catalog #MBS425706
other info2 :
Important Note: This antibody is expected to recognise isoform 1 (NP_004449.1) and isoform 2 (NP_075266.1).
ncbi acc num :
NP_004449.1
ncbi gb acc num :
NM_004458.2
ncbi mol weight :
74,436 Da
ncbi pathways :
Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Fatty Acid Beta Oxidation Pathway 198865!!Fatty Acid Biosynthesis Pathway 198873!!Fatty Acyl-CoA Biosynthesis Pathway 106115!!Fatty Acid Biosynthesis Pathway 82933!!Fatty Acid Biosynthesis Pathway 294!!Fatty Acid Degradation Pathway 82935!!Fatty Acid Degradation Pathway 296!!Fatty Acid Metabolism Pathway 868084
ncbi summary :
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]