Goat anti-CD32 / FCGR2B Antibody | MyBioSource MBS420954 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-CD32 / FCGR2B Antibody

catalog :

MBS420954

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420954

products type :

Antibody

products full name :

Goat anti-CD32 / FCGR2B Antibody

products short name :

CD32/FCGR2B

products name syn :

FCGR2B; CD32; FCG2; FCGR2; IGFR2; Fc fragment of IgG; low affinity IIb; receptor for (CD32); Fc gamma RIIb; Fc fragment of IgG; low affinity II; receptor for (CD32); Fc fragment of IgG; low affinity IIb; receptor (CD32); CD32B; Fc fragment of IgG; low affinity IIb; receptor; FCGR2B; CD32; FCG2; FCGR2; IGFR2; Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma RIIb; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); CD32B; Fc fragment of IgG, low affinity IIb, receptor

other names :

low affinity immunoglobulin gamma Fc region receptor II-b isoform 1; Low affinity immunoglobulin gamma Fc region receptor II-b; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD_antigen: CD32

products gene name :

FCGR2B

other gene names :

FCGR2B; FCGR2B; CD32; FCG2; CD32B; FCGR2; IGFR2; CD32; FCG2; IGFR2; IgG Fc receptor II-b; Fc-gamma-RIIb; FcRII-b

uniprot entry name :

FCG2B_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human

sequence length :

310

sequence :

PDALEEPDDQNRI

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Immunohistochemistry: In paraffin embedded Human Liver shows membranous staining in endothelial cells between the hepatocytes. Similar results were obtained in Human Placenta. Recommended concentration, 3-6ug/ml. Western Blot: Approx 34kDa band observed in Human myeloid erythroblast cell line K562 and Human monocytic cell line U937 lysates (calculated MW of 34.0kDa according to NP_003992.3;). In transfected HEK293 transiently expressing CD32 a band of approx. 40kDa (glycoprotein) is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.

other info1 :

Epitope: C Terminus. Immunogen: Peptide with sequence C-PDALEEPDDQNRI, from the C Terminus of the protein sequence according to NP_003992.3; NP_001002273.1; NP_001002274.1; NP_001002275.1; NP_001177757.1. Corresponding Immunizing Peptide: Catalog #MBS425840

other info2 :

Important Note: This antibody is expected to recognise all reported isoforms (NP_001002273.1; NP_001002274.1; NP_001002275.1; NP_003992.3; NP_001177757.1).

ncbi gi num :

50511930

ncbi acc num :

NP_003992.3

ncbi gb acc num :

NM_004001.4

ncbi mol weight :

33,450 Da

ncbi pathways :

Adaptive Immune System Pathway 366160!!B Cell Receptor Signaling Pathway 198909!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!BCR Signaling Pathway 138058!!Fc Gamma R-mediated Phagocytosis Pathway 114228!!Fc Gamma R-mediated Phagocytosis Pathway 106590!!Fc-epsilon Receptor I Signaling In Mast Cells Pathway 138050!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413

ncbi summary :

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

size :

0.1 mg

price :

290 USD

more info or order :

MyBioSource product webpage