catalog number :
MBS420951
products full name :
Goat anti-EXOC7 Antibody
products short name :
EXOC7
products name syn :
EXOC7; exocyst complex component 7; HGNC:23214; 2-5-3p; EXO70; Exo70p; YJL085W; EXOC7; exocyst complex component 7; HGNC:23214; 2-5-3p; EXO70; Exo70p; YJL085W
other names :
exocyst complex component 7 isoform 1; Exocyst complex component 7; exocyst complex component 7; exocyst complex component Exo70; exocyst complex component 7; Exocyst complex component Exo70
products gene name :
EXOC7
other gene names :
EXOC7; EXOC7; EX070; EXO70; EXOC1; 2-5-3p; Exo70p; YJL085W; EXO70; KIAA1067
uniprot entry name :
EXOC7_HUMAN
reactivity :
Human, Mouse, Rat, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Adrenal Gland shows staining of cytoplasm membranes and cytoplasm of secretory cells in the medulla. Recommended concentration, 5-10ug/ml. Western Blot: Approx 70kDa band observed in Human Lung lysates (calculated MW of 74.7kDa according to NP_056034.2). Recommended concentration: 0.5-1.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-DNIKNDPDKEYN, from the internal region of the protein sequence according to NP_001013861.1; NP_056034.2; NP_001138769.1; NP_001138771.1; NP_001138770.1. Corresponding Immunizing Peptide: Catalog #MBS426197
other info2 :
Important Note: This antibody is expected to recognise all five reported isoforms (NP_001013861.1; NP_056034.2; NP_001138769.1; NP_001138771.1; NP_001138770.1).
ncbi acc num :
NP_001013861.1
ncbi gb acc num :
NM_001013839.3
ncbi mol weight :
80,650 Da
ncbi pathways :
Arf6 Trafficking Events Pathway 137954!!CDC42 Signaling Events Pathway 137994!!Insulin Pathway 138026!!Insulin Processing Pathway 105903!!Insulin Signaling Pathway 83090!!Insulin Signaling Pathway 501!!Membrane Trafficking Pathway 106160!!Metabolism Of Proteins Pathway 106230!!Peptide Hormone Metabolism Pathway 771603!!Translocation Of GLUT4 To The Plasma Membrane Pathway 685554
ncbi summary :
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]