This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-AIRE (isoform 1) Antibody
catalog :
MBS420944
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, rat, dog, cow
application :
western blot, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS420944
products type :
Antibody
products full name :
Goat anti-AIRE (isoform 1) Antibody
products short name :
AIRE
products name syn :
AIRE; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); AIRE1; APECED; APS1; APSI; PGA1; autoimmune regulator (APECED protein); autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE; Goat Anti-AIRE (isoforms 1 and 2); autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); AIRE1; APECED; APS1; APSI; PGA1; autoimmune regulator (APECED protein); autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE
other names :
autoimmune regulator; Autoimmune regulator; autoimmune regulator; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; APECED protein
products gene name :
AIRE
other gene names :
AIRE; AIRE; APS1; APSI; PGA1; AIRE1; APECED; APECED; APECED protein
uniprot entry name :
AIRE_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Rat, Dog, Cow, Pig
sequence length :
545
sequence :
KDVDLSQPRKGRKP
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Thymus shows nuclear staining in select thymocytes. This product was confirmed in IHC on fetal Pig Thymus (PMID: 24770647). Recommended concentration, 2.5ug/ml. Western Blot: Appr. 60kDa in transfected HEK293 lysates (calculated MW of 57.7kDa according to NP_000374.1). Recommended concentration: 0.5-1.0 ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-KDVDLSQPRKGRKP, from the internal region of the protein sequence according to NP_000374.1. Corresponding Immunizing Peptide: Catalog #MBS428171
other info2 :
Important Note: This antibody is expected to recognise isoform 1 (NP_000374.1) only.
ncbi gi num :
4557291
ncbi acc num :
NP_000374.1
ncbi gb acc num :
NM_000383.3
ncbi mol weight :
36,501 Da
ncbi pathways :
Primary Immunodeficiency Pathway 83125!!Primary Immunodeficiency Pathway 537!!Ubiquitin Mediated Proteolysis Pathway 83056!!Ubiquitin Mediated Proteolysis Pathway 466
ncbi summary :
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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