This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Serotonin receptor 2C / HTR2C Antibody
catalog :
MBS420937
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, enzyme immunoassay
product information
catalog number :
MBS420937
products type :
Antibody
products full name :
Goat anti-Serotonin receptor 2C / HTR2C Antibody
products short name :
Serotonin receptor 2C/HTR2C
products name syn :
HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C; HGNC:5295; 5-HT2C; HTR1C; RP11-810O3.1; 5-HTR2C; OTTHUMP00000023868; serotonin 5-HT-2C receptor; serotonin receptor 2C; HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C; HGNC:5295; 5-HT2C; HTR1C; RP11-810O3.1; 5-HTR2C; OTTHUMP00000023868; serotonin 5-HT-2C receptor; serotonin receptor 2C
other names :
5-hydroxytryptamine receptor 2C isoform a; 5-hydroxytryptamine receptor 2C; 5-hydroxytryptamine receptor 2C; 5-HT1C; 5-HT-1C; 5-HT-2C; serotonin receptor 2C; serotonin 5-HT-2C receptor; 5-hydroxytryptamine receptor 1C; 5-hydroxytryptamine receptor-1c; 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled; 5-hydroxytryptamine receptor 1C; 5-HT-1C; 5-HT1C; Serotonin receptor 2C
products gene name :
HTR2C
other gene names :
HTR2C; HTR2C; HTR1C; 5-HT2C; 5HTR2C; 5-HTR2C; HTR1C; 5-HT-2C; 5-HT2C; 5-HTR2C; 5-HT-1C; 5-HT1C
uniprot entry name :
5HT2C_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence length :
458
sequence :
QVENLELPVN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 50kDa band observed in lysates of Human EBV immortalised Lymphoblastoids, T cell MOLT4 and monocytic cell line U937 (calculated MW of 51.8kDa according to NP_000859.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QVENLELPVN, from the internal region of the protein sequence according to NP_000859.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425363
ncbi gi num :
4504541
ncbi acc num :
NP_000859.1
ncbi gb acc num :
NM_000868.2
ncbi mol weight :
28,055 Da
ncbi pathways :
Amine Ligand-binding Receptors Pathway 106363!!Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Gap Junction Pathway 83072!!Gap Junction Pathway 483
ncbi summary :
Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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