catalog number :
MBS420932
products full name :
Goat anti-GRAP2 / GRID / Grf40 Antibody
products short name :
GRAP2/GRID/Grf40
products name syn :
GRAP2; GRID; P38; GADS; GRPL; GrbX; Mona; GRB2L; GRBLG; GRAP-2; GRB2-related adaptor protein 2; GRB-2-like protein; SH3-SH2-SH3 adaptor molecule; growth factor receptor-binding protein; GRB2-related protein with insert domain; hematopoietic cell-associated adaptor protein GRPL; growth factor receptor-bound protein 2-related adaptor protein 2; RP3-370M22.1; Grf40; Mona; GRAP2; GRID; P38; GADS; GRPL; GrbX; Mona; GRB2L; GRBLG; GRAP-2; GRB2-related adaptor protein 2; GRB-2-like protein; SH3-SH2-SH3 adaptor molecule; growth factor receptor-binding protein; GRB2-related protein with insert domain; hematopoietic cell-associated adaptor protein GRPL; growth factor receptor-bound protein 2-related adaptor protein 2; RP3-370M22.1; Grf40; Mona
other names :
GRB2-related adapter protein 2 isoform 1; GRB2-related adapter protein 2; GRB2-related adapter protein 2; grf-40; GRB-2-like protein; adapter protein GRID; grf40 adapter protein; SH3-SH2-SH3 adapter Mona; SH3-SH2-SH3 adaptor molecule; growth factor receptor-binding protein; GRB2-related protein with insert domain; hematopoietic cell-associated adapter protein GrpL; hematopoietic cell-associated adaptor protein GRPL; growth factor receptor-bound protein 2-related adaptor protein 2; GRB2-related adaptor protein 2; Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter Mona
products gene name :
GRAP2
other gene names :
GRAP2; GRAP2; P38; GADS; GRID; GRPL; GrbX; Mona; GRB2L; GRBLG; Grf40; GRAP-2; GADS; GRB2L; GRID; GRB2L; Grf-40
uniprot entry name :
GRAP2_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 38kDa band observed lysates of cell line Jurkat (calculated MW of 37.9kDa according to NP_004801.1). In transfected HEK293 transiently expressing GRAP2 a band of approx. 40kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-GLFPANYVAPMTR, from the C Terminus of the protein sequence according to NP_004801.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425763
ncbi acc num :
NP_004801.1
ncbi gb acc num :
NM_004810.3
ncbi mol weight :
24,382 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!CD28 Co-stimulation Pathway 119553!!Costimulation By The CD28 Family Pathway 119552!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!FCERI Mediated Ca+2 Mobilization Pathway 833827!!FCERI Mediated MAPK Activation Pathway 833826!!Fc Epsilon Receptor (FCERI) Signaling Pathway 833825!!Generation Of Second Messenger Molecules Pathway 106417!!Immune System Pathway 106386
ncbi summary :
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]