Goat anti-ADH5 Antibody | MyBioSource MBS420931 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-ADH5 Antibody

catalog :

MBS420931

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420931

products type :

Antibody

products full name :

Goat anti-ADH5 Antibody

products short name :

ADH5

products name syn :

ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide; ADH-3; ADHX; FDH; Alcohol dehydrogenase (class III), chi polypeptide; class III alcohol dehydrogenase 5 chi subunit; formaldehyde dehydrogenase; glutathione-dependent formaldehyde dehydrogenase; ADH5 antibody; alcohol dehydrogenase 5 (class III); chi polypeptide antibody; ADH-3 antibody; ADHX antibody; FDH antibody; Alcohol dehydrogenase (class III); chi polypeptide antibody; class III alcohol dehydrogenase 5 chi subunit antibody; formaldehyde dehydrogenase antibody; glutathione-dependent formaldehyde dehydrogenase antibody; GSNOR antibody

other names :

alcohol dehydrogenase class-3; Alcohol dehydrogenase class-3; alcohol dehydrogenase class-3; alcohol dehydrogenase 5 (class III), chi polypeptide; Alcohol dehydrogenase 5; Alcohol dehydrogenase class chi chain; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase (EC:1.1.1.-); FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase (EC:1.1.1.284)

products gene name :

ADH5

other gene names :

ADH5; ADH5; FDH; ADHX; ADH-3; FALDH; GSNOR; GSH-FDH; HEL-S-60p; FALDH; FDH; GSH-FDH

uniprot entry name :

ADHX_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow

sequence length :

374

sequence :

KKIKVDEFVTHN

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 4000. Immunohistochemistry: An anonymous customer found positive results in IHC on Rat penile tissue. Western Blot: Approx 38kDa band observed in Human Testis lysates (calculated MW of 39.7kDa according to NP_000662.3). Recommended concentration: 0.5-1.5ug/ml. An anonymous customer found positive results in WB on Rat penis tissue. An anonymous customer found positive results in WB on Mouse penile tissue.

other info1 :

Immunogen: Peptide with sequence C-KKIKVDEFVTHN, from the internal region of the protein sequence according to NP_000662.3. Epitope: Internal region

ncbi gi num :

71565154

ncbi acc num :

NP_000662.3

ncbi gb acc num :

NM_000671.4

ncbi mol weight :

39,724 Da

ncbi pathways :

Biological Oxidations Pathway (1270189); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Chemical Carcinogenesis Pathway (673221); Chemical Carcinogenesis Pathway (673237); Drug Metabolism - Cytochrome P450 Pathway (83032); Drug Metabolism - Cytochrome P450 Pathway (427); Ethanol Oxidation Pathway (1270206); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296)

ncbi summary :

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]

uniprot summary :

ADH5: Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. Protein type: Lipid Metabolism - fatty acid; Amino Acid Metabolism - tyrosine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.1.1.284; Oxidoreductase; Energy Metabolism - methane; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Mitochondrial; Xenobiotic Metabolism - metabolism by cytochrome P450. Chromosomal Location of Human Ortholog: 4q23. Cellular Component: cytosol; mitochondrion. Molecular Function: alcohol dehydrogenase activity; electron carrier activity; fatty acid binding; formaldehyde dehydrogenase activity; protein homodimerization activity; S-(hydroxymethyl)glutathione dehydrogenase activity; zinc ion binding. Biological Process: ethanol oxidation; formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; positive regulation of blood pressure; respiratory system process; response to lipopolysaccharide; response to nitrosative stress; response to redox state; retinoid metabolic process

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage