catalog number :
MBS420930
products full name :
Goat anti-Rhophilin 2 (Internal) Antibody
products short name :
Rhophilin 2
products name syn :
RHPN2; p76RBE; rhophilin; Rho GTPase binding protein 2; rhophilin 2; rhophilin-2; RhoB effector; rhophilin-like protein; P76RBE; RHOBP; 76 kDa RhoB effector protein; GTP-Rho-binding protein 2; rhophilin-like Rho-GTPase binding protein; Goat Anti-Rhophilin 2 (N Terminus); RHPN2; p76RBE; rhophilin, Rho GTPase binding protein 2; rhophilin 2; rhophilin-2; RhoB effector; rhophilin-like protein; P76RBE; RHOBP; 76 kDa RhoB effector protein; GTP-Rho-binding protein 2; rhophilin-like Rho-GTPase binding protein
other names :
rhophilin-2; Rhophilin-2; rhophilin-2; rhophilin 2; GTP-Rho-binding protein 2; 76 kDa RhoB effector protein; rhophilin-like Rho-GTPase binding protein; rhophilin, Rho GTPase binding protein 2; 76 kDa RhoB effector protein; GTP-Rho-binding protein 2; p76RBE
products gene name :
RHPN2
other gene names :
RHPN2; RHPN2; RHOBP; P76RBE
uniprot entry name :
RHPN2_HUMAN
reactivity :
Human, Mouse, Rat, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Kidney shows staining of cellular membrane and cytoplasm in convoluted tubular cells. Recommended concentration 5-10ug/ml. Western Blot: Preliminary experiments gave an approx 35kDa band in Human Pancreas and Prostate lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 77kDa according to NP_149094.2. The 35kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-TNKNRQKSAST, from the internal region of the protein sequence according to NP_149094.3.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426248
ncbi acc num :
NP_149094.3
ncbi gb acc num :
NM_033103.4
ncbi mol weight :
59,998 Da
ncbi pathways :
G13 Signaling Pathway 198800
ncbi summary :
This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]