product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-KCC4/SLC12A7 Antibody
catalog :
MBS420915
quantity :
0.1 mg
price :
225 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420915
products type :
Antibody
products full name :
Goat anti-KCC4/SLC12A7 Antibody
products short name :
KCC4/SLC12A7
products name syn :
SLC12A7; solute carrier family 12 (potassium/chloride transporters), member 7; DKFZP434F076; KCC4; potassium/chloride transporter KCC4; SLC12A7 antibody; solute carrier family 12 (potassium/chloride transporters); member 7 antibody; DKFZP434F076 antibody; KCC4 antibody; potassium/chloride transporter KCC4 antibody; KCC4 / SLC12A7
other names :
solute carrier family 12 member 7; Solute carrier family 12 member 7; solute carrier family 12 member 7; solute carrier family 12 member 7; Electroneutral potassium-chloride cotransporter 4; K-Cl cotransporter 4
products gene name :
SLC12A7
products gene name syn :
KCC4
other gene names :
SLC12A7; SLC12A7; KCC4; KCC4
uniprot entry name :
S12A7_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Expected from sequence similarity: Human, Mouse
sequence length :
1083
sequence :
QLIHDRNTASHT
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Preliminary experiments in Human Heart and Kidney lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
other info1 :
Immunogen: Peptide with sequence C-QLIHDRNTASHT, from the internal region of the protein sequence according to NP_006589.2. Epitope: Internal region
ncbi gi num :
123701900
ncbi acc num :
NP_006589.2
ncbi gb acc num :
NM_006598.2
ncbi mol weight :
28,258 Da
ncbi pathways :
Cation-coupled Chloride Cotransporters Pathway (1269912); Collecting Duct Acid Secretion Pathway (147586); Collecting Duct Acid Secretion Pathway (147560); SLC-mediated Transmembrane Transport Pathway (1269907); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway (1269908)
uniprot summary :
KCC4: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. Belongs to the SLC12A transporter family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family. Chromosomal Location of Human Ortholog: 5p15. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: potassium ion symporter activity; potassium:chloride symporter activity; protein kinase binding. Biological Process: cell volume homeostasis; ion transport; synaptic transmission; transport
size1 :
0.1 mg
price1 :
225 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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