catalog number :
MBS420913
products full name :
Goat anti-RANGAP1 Antibody
products short name :
RANGAP1
products name syn :
RANGAP1; KIAA1835; Ran GTPase activating protein 1; Fug1; MGC20266; SD; OTTHUMP00000198756; OTTHUMP00000198757; segregation distorter homolog; segregation distortion; RANGAP1; KIAA1835; Ran GTPase activating protein 1; Fug1; MGC20266; SD; OTTHUMP00000198756; OTTHUMP00000198757; segregation distorter homolog; segregation distortion
other names :
ran GTPase-activating protein 1; Ran GTPase-activating protein 1; ran GTPase-activating protein 1; segregation distortion; segregation distorter homolog; Ran GTPase activating protein 1
products gene name :
RANGAP1
other gene names :
RANGAP1; RANGAP1; SD; Fug1; RANGAP; KIAA1835; SD; RanGAP1
uniprot entry name :
RAGP1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
ASEDIAKLAETLAK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Liver shows vesicular staining in the cytoplasm of hepatocytes. Recommended concentration, 2-4ug/ml. Western Blot: Approx 70kDa band observed in Human Brain and 3T3 lysates (predicted MW of 68kDa according to NP_002874). Recommended for use at 0.1-0.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence ASEDIAKLAETLAK-C, from the N Terminus of the protein sequence according to NP_002874.1. Corresponding Immunizing Peptide: Catalog #MBS426733
other info2 :
Important Note: Please note that in mouse, there is a hypothetical protein called "similar to RANGAP1" (XP_139737.2) that is virtually identical.
ncbi acc num :
NP_002874.1
ncbi gb acc num :
NM_002883.3
ncbi mol weight :
63,542 Da
ncbi pathways :
Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Disease Pathway 530764!!HIV Infection Pathway 105983!!HIV Life Cycle Pathway 105984!!Host Interactions Of HIV Factors Pathway 106010!!Interactions Of Rev With Host Cellular Proteins Pathway 106014!!Late Phase Of HIV Life Cycle Pathway 105995!!M Phase Pathway 105812!!Mitotic Anaphase Pathway 105818
ncbi summary :
This gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP)-binding and exchange. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]