Goat anti-Ku80 / XRCC5 Antibody | MyBioSource MBS420912 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-Ku80 / XRCC5 Antibody

catalog :

MBS420912

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420912

products type :

Antibody

products full name :

Goat anti-Ku80 / XRCC5 Antibody

products short name :

Ku80/XRCC5

products name syn :

XRCC5; KU80; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining Ku autoantigen; 80kDa); HGNC:12833; KARP-1; KARP1; Ku86; NFIV; ATP-dependent DNA helicase II; DNA repair protein XRCC5; Ku86 autoantigen related protein 1; Ku autoantigen; 80kD; X-ray repair; complementing defective; repair in Chinese hamster; XRCC5; KU80; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining Ku autoantigen, 80kDa); HGNC:12833; KARP-1; KARP1; Ku86; NFIV; ATP-dependent DNA helicase II; DNA repair protein XRCC5; Ku86 autoantigen related protein 1; Ku autoantigen, 80kD; X-ray repair, complementing defective, repair in Chinese hamster

other names :

X-ray repair cross-complementing protein 5; X-ray repair cross-complementing protein 5; X-ray repair cross-complementing protein 5; TLAA; CTC85; CTCBF; nuclear factor IV; Ku autoantigen, 80kDa; DNA repair protein XRCC5; thyroid-lupus autoantigen; 86 kDa subunit of Ku antigen; lupus Ku autoantigen protein p86; Ku86 autoantigen related protein 1; CTC box-binding factor 85 kDa subunit; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining); 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

products gene name :

XRCC5

other gene names :

XRCC5; XRCC5; KU80; KUB2; Ku86; NFIV; KARP1; KARP-1; G22P2; CTC85; CTCBF; TLAA

uniprot entry name :

XRCC5_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human

sequence length :

732

sequence :

SLAKKDEKTDTLED

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Western Blot: Approx 80-85kDa band observed in lysates of HeLa (calculated MW of 82.7kDa according to NP_066964.1). Recommended concentration: 0.1-0.3ug/ml. An additional band of 75kDa was observed consistent with products from other sources. Peptide ELISA: antibody detection limit dilution 1:16000.

other info1 :

Epitope: Internal Region. Immunogen: Peptide with sequence C-SLAKKDEKTDTLED, from the internal region of the protein sequence according to NP_066964.1.

other info2 :

Corresponding Immunizing Peptide: Catalog #MBS425330

ncbi gi num :

10863945

ncbi acc num :

NP_066964.1

ncbi gb acc num :

NM_021141.3

ncbi mol weight :

82,705 Da

ncbi pathways :

2-LTR Circle Formation Pathway 105993!!BARD1 Signaling Events Pathway 137959!!Coregulation Of Androgen Receptor Activity Pathway 138085!!Cytosolic Sensors Of Pathogen-associated DNA Pathway 576255!!DNA Repair Pathway 105837!!DNA-PK Complex Pathway 413430!!DNA-PK Complex Pathway 890556!!Disease Pathway 530764!!Double-Strand Break Repair Pathway 105861!!Early Phase Of HIV Life Cycle Pathway 105985

ncbi summary :

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

290 USD

more info or order :

MyBioSource product webpage