catalog number :
MBS420906
products full name :
Goat anti-RAC2 Antibody
products short name :
RAC2
products name syn :
RAC2; ras-related C3 botulinum toxin substrate 2 (rho family; small GTP binding protein Rac2); EN-7; Ras-related C3 botulinum toxin substrate 2; rho family; small GTP binding protein Rac2; Ras-related C3 botulinum toxin substrate 3 (rho family; small GTP-binding protein Rac2); Gx; HSPC022; small G protein; RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); EN-7; Ras-related C3 botulinum toxin substrate 2; rho family, small GTP binding protein Rac2; Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); Gx; HSPC022; small G protein
other names :
ras-related C3 botulinum toxin substrate 2; Ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2; small G protein; Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); GX; Small G protein; p21-Rac2
products gene name :
RAC2
other gene names :
RAC2; RAC2; Gx; EN-7; HSPC022; p21-Rac2
uniprot entry name :
RAC2_HUMAN
reactivity :
Human, Mouse, Rat
sequence :
PQPTRQQKRACSLL
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Tonsil, stains most cells in the mantle zone and interfollicular area. In the germinal centres the majority of cells are negative. Recommended concentration 0.3ug/ml. Data were obtained from a previous batch. Western Blot: Approx 20kDa band observed in lysates of Human Tonsil lysate (calculated MW of 21.4kDa according to NP_002863.1). Recommended concentration: 0.1-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence PQPTRQQKRACSLL, from the C Terminus of the protein sequence according to NP_002863.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425596
ncbi acc num :
NP_002863.1
ncbi gb acc num :
NM_002872.4
ncbi mol weight :
21,429 Da
ncbi pathways :
Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Axon Guidance Pathway 83065!!Axon Guidance Pathway 476!!Axon Guidance Pathway 105688!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Colorectal Cancer Pathway 83106
ncbi summary :
This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]