product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-GEF5 Antibody
catalog :
MBS420902
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420902
products type :
Antibody
products full name :
Goat anti-GEF5 Antibody
products short name :
GEF5
products name syn :
GEF5; DKFZp686N1969; ARHGEF5; Rho guanine nucleotide exchange factor (GEF) 5; P60; TIM; TIM1; guanine nucleotide regulatory protein TIM; oncogene TIM rho guanine nucleotide exchange factor 5; transforming immortalized mammary oncogene; GEF5 antibody; DKFZp686N1969 antibody; ARHGEF5 antibody; Rho guanine nucleotide exchange factor (GEF) 5 antibody; P60 antibody; TIM antibody; TIM1 antibody; guanine nucleotide regulatory protein TIM antibody; oncogene TIM rho guanine nucleotide exchange factor 5 antibody; transforming immortalized mammary oncogene antibody
other names :
rho guanine nucleotide exchange factor 5; Rho guanine nucleotide exchange factor 5; rho guanine nucleotide exchange factor 5; Rho guanine nucleotide exchange factor 5; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM
products gene name :
ARHGEF5
products gene name syn :
GEF5
other gene names :
ARHGEF5; ARHGEF5; P60; TIM; GEF5; TIM1; TIM
uniprot entry name :
ARHG5_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human
sequence length :
1597
sequence :
DKEIDQNSQQEE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Approx 170kDa band observed in Human HeLa lysates (calculated MW of 177kDa according to NP_005426.2). Recommended concentration: 0.1-0.3ug/ml.
other info1 :
Immunogen: Peptide with sequence C-DKEIDQNSQQEE, from the internal region of the protein sequence according to NP_005426.2. Epitope: Internal region
ncbi gi num :
50959191
ncbi acc num :
NP_005426.2
ncbi gb acc num :
NM_005435.3
ncbi mol weight :
60,056 Da
ncbi pathways :
Regulation Of RhoA Activity Pathway (138070)
ncbi summary :
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]
uniprot summary :
ARHGEF5: 2 isoforms of the human protein are produced by alternative splicing. Protein type: GEFs; Motility/polarity/chemotaxis; Oncoprotein; GEFs, Rac/Rho. Chromosomal Location of Human Ortholog: 7q35. Cellular Component: cell junction; cell projection; cytoplasm; nucleoplasm; nucleus; plasma membrane; podosome. Molecular Function: GTP binding; guanyl-nucleotide exchange factor activity; lipid binding; protein binding; Rho guanyl-nucleotide exchange factor activity. Biological Process: actin cytoskeleton organization and biogenesis; myeloid dendritic cell chemotaxis; positive regulation of GTPase activity; positive regulation of JNK activity; positive regulation of stress fiber formation; positive regulation of transcription factor activity; regulation of actin cytoskeleton organization and biogenesis; regulation of cytoskeleton organization and biogenesis; regulation of GTPase activity; regulation of Rho protein signal transduction
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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